
杏仁核神经环路在调控焦虑行为中的作用机制研究进展|焦虑|BLA
2021年11月2日 · 前额叶皮质(prefrontal cortex, PFC)是大脑中调节情感功能的重要脑区之一,前额叶对杏仁核“自上而下”的输入对于维持正常的情感活动具有十分重要的作用 。 在动物 …
Prefrontal Cortex Drives Distinct Projection Neurons in the …
2017年11月7日 · We characterize PFC inputs onto three distinct populations of BLA neurons that project to the PFC, ventral hippocampus, or nucleus accumbens. We find that PFC-evoked …
【文献解读】mPFC-杏仁核介导焦虑 - 知乎 - 知乎专栏
bla是调节焦虑相关状态和行为的神经环路中的一个关键脑区。bla由兴奋性投射组成神经元(pns,约80-90%)和抑制性神经元(约10–20%),兴奋性神经元通-7过中间能神经元的精细 …
A neuronal circuit for activating descending modulation of ... - Nature
2019年9月9日 · It was shown that nerve injury strengthens synaptic input from the BLA onto inhibitory interneurons located in the prelimbic medial PFC, by virtue of reduced …
Rostral and caudal basolateral amygdala engage distinct ... - eLife
2022年12月7日 · The prelimbic and infralimbic prefrontal cortex (PFC) process distinct inputs from rostral and caudal basolateral amygdala (BLA), which engage different populations of …
BLA-involved circuits in neuropsychiatric disorders
2024年8月1日 · Inactivation of the BLA could reversely prevent chronic stress-induced volume loss of PFC, alleviate metabolic disorders of PFC monoaminergic systems, and prevent …
内侧前额叶皮层-基底外侧杏仁核投射神经元分层亚群的解剖学研究
Objective ·To dissect the fine anatomical structure of medial prefrontal cortex (mPFC)-basolateral amygdala (BLA) projection neurons based on regional and laminar specificity in the cortex in...
文献精读 | 激活神经病理性疼痛下行调控的神经环路_澎湃号·湃客_ …
本研究使用光遗传学方法来检验特定谷氨酸能BLA输入mPFC的作用,揭示mPFC信号处理失调的分子基础,并阐明涉及慢性神经病理性疼痛状态的下游大脑回路。 1、神经损伤引起BLA …
Inhibitory Gating of Basolateral Amygdala Inputs to the …
2016年9月7日 · The prefrontal cortex (PFC) and basolateral amygdala (BLA) interact to control emotional behaviors. Here we show that BLA inputs elicit direct excitation and feedforward …
Prefrontal Cortex Drives Distinct Projection Neurons in the …
2017年11月7日 · The prefrontal cortex (PFC) regulates emotional behavior via top-down control of the basolateral amygdala (BLA). However, the influence of PFC inputs on the different …