PFKFB3 Gene - GeneCards | F263 Protein | F263 Antibody
2024年12月25日 · PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3) is a Protein Coding gene. Diseases associated with PFKFB3 include Colon Adenocarcinoma and …
Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on …
PFKFB3 levels affect angiogenesis through mediating VEGF activity, where PFKFB3 upregulation results in enhanced VEGF activity. Moreover, silencing of PFKFB3 impairs angiogenesis, …
Roles of PFKFB3 in cancer - Signal Transduction and Targeted …
2017年11月24日 · In this review, we summarize current knowledge of PFKFB3 regulation by several signal pathways and its function in cancer development in different cell types in cancer …
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKFB3 is an essential target of EGFR signaling and that PFKFB3 activation is required for glycolysis stimulation upon EGFR activation. PFKFB3 has a key role in mediating glucose …
Roles of PFKFB3 in cancer - PMC - PubMed Central (PMC)
In this review, we summarize current knowledge of PFKFB3 regulation by several signal pathways and its function in cancer development in different cell types in cancer tissues. Ubiquitous …
6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle ... - Nature
2014年7月17日 · In this study, we demonstrate that siRNA silencing of endogenous PFKFB3 inhibits Cdk1 activity, which in turn stabilizes p27 protein levels causing cell cycle arrest at …
PFKFB3 regulates cancer stemness through the hippo pathway in …
2022年7月8日 · PFKFB3 (6-phosphofructo-2-kinase) is the rate-limiting enzyme of glycolysis and is overexpressed in several human cancers that are associated with poor prognosis. High …
PFKFB3, a key glucose metabolic enzyme regulated by pathogen ...
PFKFB3 encodes 6-phosphofructo-2-kinase/fructose-2, and 6-biphosphatase 3 enzyme (PFK-2/FBPase-2) in humans. PFK-2/FBPase-2 is a bi-functional enzyme that controls glycolytic flux …
Roles of PFKFB3 in cancer - PubMed
2017年11月24日 · In this review, we summarize current knowledge of PFKFB3 regulation by several signal pathways and its function in cancer development in different cell types in cancer …
Nuances of PFKFB3 Signaling in Breast Cancer - ScienceDirect
2022年6月1日 · PFKFB3 links external stimuli to cellular responses via kinase cascades. Anti-PFKFB3 therapy has a suppressive effect over cell functions due to various mechanisms. The …
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