2017年11月30日 · 副流感病毒（PIV）是一类具有多形性、有包膜的单股负链 RNA 病毒，属副黏病毒，分为 4 种亚型，PIV-1 和 PIV-3 属于呼吸道病毒属，而 PIV-2 和 PIV-4 属于腮腺炎病毒属。 病毒直径 125-250 nm，包膜由脂质和糖蛋白组成。 糖蛋白有两种：一种为血球凝集素-神经氨酶蛋白（NH），具有红细胞凝集活性和神经氨酶活性；另一种为融合蛋白（F 蛋白），具有促进细胞融合的作用和溶血特性。 PIV 所致疾病的发病机制是由病毒复制和宿主免疫应答所介导。 高水 …

Parainfluenza virus (PIV) is a leading cause of lower respiratory tract infections. Although there are several distinct PIV serotypes, few studies have compared the clinical characteristics and severity of infection among the individual PIV serotypes and between PIV and other pathogens in patients with community-acquired pneumonia.

Human parainfluenza virus (PIV) type 3 infections are the second most common cause of serious respiratory tract disease in infants and children (after RSV). Each year, approximately 25% of children <5 years of age experience a clinically significant PIV infection and 2% of them require hospitalization. This virus subtype commonly causes ...

2023年8月21日 · Parainfluenza viruses (PIVs) are important respiratory pathogens in adults and children. Although parainfluenza viruses are commonly recognized as a significant cause of morbidity and mortality in children, their impact in adults is less well characterized [1].

2019年1月7日 · Differences in seasonality, clinical presentation, and prevalence between the different PIV serotypes (PIV-1, PIV-2, and PIV-3) were identified. The most common signs/symptoms were cough (88%), productive sputum (55%), fever (63%), and dyspnea (49%).

2023年8月21日 · 在成人中，PIV通常引起轻度上呼吸道感染(upper respiratory infection, URI)，但也可导致危及生命的下呼吸道感染，特别是在免疫功能低下的患者中。 本文将总结成人PIV感染的病毒学、临床表现、诊断和治疗。

2024年7月22日 · 副流感病毒（parainfluenza viruses，PIV）隶属副黏病毒科，为单链RNA病毒，电镜下多呈球型，直径125～250 nm，约有15500个核苷酸，编码6种结构蛋白。 PIV主要侵犯呼吸道黏膜的表层组织，在纤毛上皮细胞内复制和繁殖。

2009年3月3日 · Human PIV-2 Recombinant Sendai Virus (rSeV) Elicits Durable Immunity and combines with two additional rSeVs to protect against hPIV-1, hPIV-2, hPIV-3, and RSV

2023年10月26日 · piv年检出率为14.9%，高峰期为4月至9月。与其他年龄组相比，一岁以下儿童的 piv 感染率最高（45.5%）。在121个测序样本中，piv-3、piv-1和piv-2阳性率分别为58.7%、36.4%和4.9%，未检测到piv-4。严重感染与先前存在的基础疾病和合并感染有关，但与 piv 血清型 …

Human parainfluenza type 2 virus (HPIV2) is a member of the genus Rubulavirus of the family paramyxoviridae, and it possesses a single-stranded, nonsegmented, and negative-stranded RNA genome that encodes seven viral proteins from six genes …