In 2019, PNOC established disease specific “working groups” with the main intent to bring clinicians, scientists, philanthropy, and families together to enhance clinical trial development …

Inclusion Criteria: – Participants must have either a molecularly or histologically confirmed embryonal tumor with multilayered rosettes. – For enrollment, a confirmation of a minimum of …

PNOC is proud of the exceptional commitment and work of our sites across the United States, the Australian & New Zealand Children’s Haematology/Oncology Group, Canada, Egypt, Europe, …

Pediatric Brain Center. Ron Conway Family Gateway Medical Building. 1825 Fourth Street, 6th Floor. San Francisco, CA 94158. Get Directions

About PNOC. Our Core Values are driven by the need to quickly address the significant unmet need of children and young adults with CNS tumors with a set of guiding principles.

The Pediatric Neuro-Oncology Consortium (PNOC) was formed in 2012 to improve the overall and quality outcomes for children and young adults with central nervous systems (CNS) tumors.

Inclusion Criteria. Participants must have a pathologic diagnosis of ATRT. The diagnosis must be supported by (1) immunohistochemistry demonstrating loss of INI1 or BRG1 or (2) …

Division of Pediatric Hematology/Oncology Mattel Children’s Hospital UCLA 10833 Le Conte Avenue Los Angeles, CA 90095-1752 USA

The rationale for this protocol is to provide a framework to collect comprehensive outcome data on children and young adults with primary central nervous system tumors to inform cognitive, …

To measure the relative changes in cell cycle-related genetic signature of the tumor microenvironment post administration of neoadjuvant nivolumab in children and young adults …