2018年11月8日 · In the last decade, development of point-of-care platforms (POCs) for diagnosis of infectious diseases or rapid tests (RTs) has increased in order to attend to the need for reliable diagnostic tests for surveillance of endemic areas.

2021年6月16日 · Commercially available point-of-care circulating cathodic antigen (POC-CCA) cassette tests detect schistosomiasis antigens from urine samples in 20 minutes. POC-CCA results are qualitative or semi-quantitative: signal intensity is an indicator of the amount of worm antigens in the sample.

The POC-CCA assay for detection of Schistosoma mansoni infection needs standardization in production and proper quality control to be reliable

We aimed to compare the performance of an immunological assay, the point-of-care circulating cathodic antigen (POC-CCA®) test, with that of two parasitological techniques in a low-endemicity population.

2024年1月1日 · Point-of-care (POC) lateral flow immunoassays (LFIAs) have been widely developed and assessed for the screening of schistosomiasis. Recent advances have rapidly facilitated the development of molecular-based POC diagnostics for schistosomiasis.

This article describes multiple SCORE-funded studies comparing the POC-CCA and KK assays, the pros and cons of these assays, the use of the POC-CCA assay for mapping of S. mansoni infections in areas across the spectrum of prevalence levels, and the validation and recognition that the POC-CCA, although not infallible, is a highly useful tool to ...

We have assessed the positivity rate of S. mansoni infection in Bananeiras, a village on Capistrano, Ceara, Brazil by performing a point-of-care test in urine to determine the circulating cathodic antigens (POC-CCA), and we compared the findings with those of the Kato-Katz technique for egg detection in stool and an enzyme-linked immunosorbent ...

2020年9月25日 · This study aimed to evaluate the point-of-care circulating cathodic antigen (POC-CCA) test performance using sensitive parasitological methods as a reference standard (RS) in individuals before and after treatment.

POC-CCA®, an immunochromatography-based test that identifies the circulating cathodic antigen (CCA) of the parasite in urine samples of positive individuals, also presents a persistent low ...

2020年8月12日 · We validated the POC-CCA test’s ability to diagnose Schistosoma mekongi infection in Lao People’s Democratic Republic (Lao PDR), where S. mekongi is endemic. Of particular interest was the test’s specificity and possible cross …