
The role of PPARγ-mediated signalling in skin biology and ... - PubMed
This includes a role in mediating skin and pilosebaceous unit homoeostasis: PPARs appear to be essential for maintaining skin barrier permeability, inhibit keratinocyte cell growth, promote …
New Insights into the Role of PPARγ in Skin Physiopathology
The PPAR family, through its ability to modulate inflammatory response and antioxidant defense, can modulate the balance between MMP activity and collagen expression to maintain skin …
Peroxisome proliferator-activated receptors (PPARs) in skin …
2007年8月1日 · The present review summarizes our current knowledge of PPAR functions in rodent and human skin. The roles of PPARα, β and γ in the healthy skin, including embryonic …
过氧化物酶体增殖激活受体(ppar)是配体激活的转录因子,属于核激素受体家族。s ppar具有s3种亚型: ppar、αpparβ/δ和pparγ,具有不同组织分布和细胞功能。3种ppars亚型均在皮肤中有 …
The role of PPAR γ -mediated signalling in skin biology and …
2015年2月3日 · This includes a role in mediating skin and pilosebaceous unit homoeostasis: PPARs appear to be essential for maintaining skin barrier permeability, inhibit keratinocyte cell …
Peroxisome Proliferator-Activated Receptors (PPARs) and the Human Skin
2012年9月10日 · Because of their diverse biologic activities on keratinocytes and other skin cells, PPARs represent a major research target for the understanding and treatment of many skin …
Peroxisome proliferator-activated receptors (PPARs) in …
The present review summarizes the current knowledge of PPAR functions in various skin disorders particularly those involving inflammation and epidermal hyperproliferation (i.e., …
PPAR——皮肤屏障修复过程中必不可少的蛋白 - 知乎
过氧化物酶体增殖物激活受体 (PPAR)是多向性调控巨噬细胞参与屏障修复每个阶段的转录因子,属于细胞核激素受体超级家族,有PPARα、PPARγ以及PPARβ/δ三个亚型。 PPAR的三种 …
Peroxisome proliferator-activated receptors (PPARs) and the human skin …
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that regulate lipid, glucose, and amino acid metabolism. More recently, PPARs …
New Insights into the Role of PPARγ in Skin …
2024年6月19日 · Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor expressed in many tissues, including skin, where it is essential for maintaining skin …