This includes a role in mediating skin and pilosebaceous unit homoeostasis: PPARs appear to be essential for maintaining skin barrier permeability, inhibit keratinocyte cell growth, promote …

The PPAR family, through its ability to modulate inflammatory response and antioxidant defense, can modulate the balance between MMP activity and collagen expression to maintain skin …

2007年8月1日 · The present review summarizes our current knowledge of PPAR functions in rodent and human skin. The roles of PPARα, β and γ in the healthy skin, including embryonic …

过氧化物酶体增殖激活受体(ppar)是配体激活的转录因子，属于核激素受体家族。s ppar具有s3种亚型： ppar、αpparβ/δ和pparγ，具有不同组织分布和细胞功能。3种ppars亚型均在皮肤中有 …

2015年2月3日 · This includes a role in mediating skin and pilosebaceous unit homoeostasis: PPARs appear to be essential for maintaining skin barrier permeability, inhibit keratinocyte cell …

2012年9月10日 · Because of their diverse biologic activities on keratinocytes and other skin cells, PPARs represent a major research target for the understanding and treatment of many skin …

The present review summarizes the current knowledge of PPAR functions in various skin disorders particularly those involving inflammation and epidermal hyperproliferation (i.e., …

过氧化物酶体增殖物激活受体 （PPAR）是多向性调控巨噬细胞参与屏障修复每个阶段的转录因子，属于细胞核激素受体超级家族，有PPARα、PPARγ以及PPARβ/δ三个亚型。 PPAR的三种 …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that regulate lipid, glucose, and amino acid metabolism. More recently, PPARs …

2024年6月19日 · Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor expressed in many tissues, including skin, where it is essential for maintaining skin …