
The PPARgene database - Home
PPARgene database is not only a resource that curated the experimentally verified PPAR-α, -β/δ, and -γ target genes but also a platform that integrated tool(s) for predicting novel PPAR target …
PPARα: An emerging target of metabolic syndrome, …
Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor that is involved in lipid metabolism of various tissues. Different metabolites of fatty acids and …
Peroxisome Proliferator-Activated Receptor Alpha Target Genes
The peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor involved in the regulation of a variety of processes, ranging from inflammation and …
Integrated physiology and systems biology of PPARα
2014年7月1日 · The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription factor that plays a major role in metabolic regulation. This review addresses the functional role …
The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: …
Peroxisome proliferator-activated receptor-delta (PPAR-δ), one of three members of the PPAR group in the nuclear receptor superfamily, is a ligand-activated transcription factor. PPAR-δ …
PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
2018年3月20日 · This review highlights research findings on the PPARβ/δ regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. …
PPARgene: A Database of Experimentally Verified and ... - PubMed
Upon ligand binding, PPARs activate target gene transcription and regulate a variety of important physiological processes such as lipid metabolism, inflammation, and wound healing. Here, we …
PPARγ phase separates with RXRα at PPREs to regulate target …
2022年4月26日 · Peroxisome proliferator-activated receptor (PPAR)-γ is a key transcription activator controlling adipogenesis and lipid metabolism. PPARγ binds PPAR response …
Molecular mechanism of PPARα action and its impact on lipid …
2015年3月1日 · In this review, we discuss the transcriptional activation and repression mechanisms by PPARα, the spectrum of target genes and chromatin-binding maps from …
Peroxisome proliferator-activated receptor alpha target genes
The peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor involved in the regulation of a variety of processes, ranging from inflammation and …
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