2024年12月25日 · PPARGC1A (PPARG Coactivator 1 Alpha) is a Protein Coding gene. Diseases associated with PPARGC1A include Cholestasis, Benign Recurrent Intrahepatic, 2 and Aging. …

PGC-1α is a transcriptional coactivator that regulates the genes involved in energy metabolism. It is the master regulator of mitochondrial biogenesis. [6][7][8] This protein interacts with the …

PGC1 alpha（过氧化物酶体增殖物激活受体γ共激活剂1-alpha）是类固醇受体和核受体的转录共激活剂。 PGC1 alpha增加解偶联蛋白启动子上PPARG和甲状腺激素受体的转录活性。 PGC1 …

2023年9月7日 · The peroxisome proliferator-activated receptor gamma (PPARγ) coactivator 1 alpha (PGC-1α, encoded by the PPARGC1A gene) exerts a central regulatory role in sensing...

该基因编码的蛋白质是一种转录共激活因子，可调节参与能量代谢的基因。 这种蛋白质与 PPARgamma 相互作用，从而允许这种蛋白质与多种转录因子相互作用。 这种蛋白质可以与 …

2023年6月5日 · Here we provide data indicating that epigenetic suppression of PGC1α defines an aggressive subset of chronic BRAF-inhibitor treated melanomas. A metabolism-centered …

2025年2月19日 · Epigenetic suppression of PGC1alpha (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas. Engineered allele …

2025年2月11日 · Ppargc1a gene transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscle; PV expression …

2025年2月9日 · Microarray analysis indicates HIV-1 Tat-induced upregulation of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A) in primary human …

与人 ppargc1a（pparg 辅激活因子 1 α）同源。 [由基因组资源联盟提供，2022 年 4 月] Enables several functions, including alpha-tubulin binding activity; Estrogen Receptor binding activity; …