Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis. [5][6] PRC1 protein is expressed at relatively high levels …

Polycomb repressive complex 1 (PRC1) is one of the two classes of Polycomb Repressive complexes, the other being PRC2. Polycomb-group proteins play a major role in transcriptional …

2024年12月25日 · PRC1 (Protein Regulator Of Cytokinesis 1) is a Protein Coding gene. Diseases associated with PRC1 include Bladder Cancer. Among its related pathways are Signaling by …

2021年3月15日 · PcG proteins function on chromatin and can form two distinct complexes with different enzymatic activities: Polycomb repressive complex 1 (PRC1) is a histone ubiquitin …

2024年3月22日 · We propose that PRC1 composition can modulate condensate properties, providing crucial regulatory flexibility across developmental stages.

We demonstrate that PRC1, a mitotic spindle-associated Cdk substrate that is essential to cell cleavage, is a microtubule binding and bundling protein both in vivo and in vitro. …

Yeast two-hybrid experiments as well as biochemical studies have revealed that the PcG proteins assemble to form two main protein complexes called Polycomb repressive complexes 1 …

2021年8月16日 · Using single-cell gene expression analysis, we reveal that PRC1 acts uniformly within the cell population and that repression is achieved by controlling transcriptional burst …

2021年6月21日 · Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying complex that monoubiquitinates histone H2A and is involved in maintaining the repressed …

PRC1 is a nuclear protein in interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell midbody during cytokinesis.