PRDM16 Gene - GeneCards | PRD16 Protein | PRD16 Antibody
2024年12月25日 · PRDM16 (PR/SET Domain 16) is a Protein Coding gene. Diseases associated with PRDM16 include Left Ventricular Noncompaction 8 and Left Ventricular Noncompaction. …
Post-translational control of beige fat biogenesis by PRDM16 ...
2022年8月17日 · PR domain-containing 16 (PRDM16) is a dominant activator of the biogenesis of beige adipocytes by forming a complex with transcriptional and epigenetic factors and is …
Functions of Prdm16 in thermogenic fat cells - PMC - PubMed …
The PR-domain containing 16 (Prdm16) protein is a powerful inducer of the thermogenic phenotype in fat cells. In both developmental (brown) and induced (beige) thermogenic …
The Multifaceted Roles of PRDM16: Adipose Biology and Beyond
2016年1月1日 · PRDM16 is a master transcriptional coregulator in brown adipocytes. It forms complexes with various transcriptional cofactors in a promoter-dependent context, acting …
PRDM Proteins: Molecular Mechanisms in Signal Transduction and ...
PRDM16 encodes a Zn-finger protein (MEL1) that shares 63% sequence similarity to PRDM3/MECOM (MDS1 and EVI1 complex locus, also known as EVI1, MDS1).
The Multifaceted Roles of PRDM16: Adipose Biology and Beyond
2015年12月10日 · PRDM16 is a master transcriptional coregulator in brown adipocytes. It forms complexes with various transcriptional cofactors in a promoter-dependent context, acting …
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor …
2021年12月17日 · PRDM16 functioned mechanistically as a compact myocardium-enriched transcription factor that activated compact myocardial genes while repressing trabecular …
PRDM16 controls a brown fat/skeletal muscle switch - Nature
2008年8月21日 · PRDM16 stimulates brown adipogenesis by binding to PPAR-γ (peroxisome-proliferator-activated receptor-γ) and activating its transcriptional function. Finally, Prdm16 …
PRDM16 stability and metabolically healthy adipose tissue
2022年9月5日 · PRDM16 is a key mediator of thermogenic fat, counteracting adipose fibrosis and inflammation. Kajimura and co-authors demonstrate that a CUL2–APPBP2 ubiquitin E3 ligase …
PRDM16 Regulating Adipocyte Transformation and …
Positive regulatory domain zinc finger region protein 16 (PRDM16), a transcription factor that is highly expressed in adipocytes, plays a key role in adipose tissue metabolism, such as the …
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