Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. [1] .

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor (TGF)-β family of ligands with nearly thirty distinct human proteins bearing the BMP name. Important differences exist among these molecules with regard to pathway mechanics and effects on cell behavior.

Bone morphogenetic proteins (BMPs), originally identified as osteoinductive components in extracts derived from bone, are now known to play important roles in a wide array of processes during formation and maintenance of various organs including bone, cartilage, muscle, kidney, and blood vessels.

2014年9月1日 · Bone Morphogenetic Proteins (BMPs) are a group of signaling molecules that belongs to the Transforming Growth Factor-β (TGF-β) superfamily of proteins. Initially discovered for their ability to induce bone formation, BMPs are …

2020年9月1日 · Bone morphogenetic proteins (BMPs) are secreted cytokines that control the fate and function of many different cell types. They exert their cellular responses via heteromeric complexes of specific BMP type I and type II serine/threonine kinase receptors, e.g. …

2020年9月24日 · Specifically, we found that anti-PD1-resistant tumors overexpress bone morphogenetic protein (BMP)7, also known as OP-1. BMP7 is a secreted protein that belongs to the transforming growth factor...

2017年7月15日 · BMP signaling regulates multiple reproductive processes across Metazoa. Germ line specification, proliferation, migration, and gametogenesis are often BMP-dependent. Some BMP ligands play sex-specific reproductive roles in vertebrates. BMP-based PGC specification may have facilitated co-option of the pathway to other germ line roles.

2019年9月17日 · Bone morphogenetic proteins (BMPs) are multifunctional cytokines of the transforming growth factor β (TGFβ) superfamily with potential therapeutic applications due to...

Recombinant Human Bone morphogenetic protein 4 is produced by our E.coli expression system and the target gene encoding Ser293-Arg408.

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