The replicase protein nsp2 of Chinese highly pathogenic porcine ...
2023年10月13日 · The genome segment for replicase protein nsp2 represents the fastest evolving region of porcine reproductive and respiratory syndrome virus (PRRSV), and our …
猪繁殖与呼吸综合征(PRRS)是由猪繁殖与呼吸综合征病毒(PRRSV)引起的一种高度传染性疾病,主要特征是各种年龄的猪均可感染发病,出现生殖障碍和呼吸道症状,本病极易引起细菌、支原体 …
Molecular Characterization of the Nsp2 and ORF5 (ORF5a) Genes of PRRSV …
2021年3月4日 · The genetic characteristic of HP-PRRSV isolates have a discontinuous 30-amino-acid deletion in Nsp2, and NADC30-like PRRSV isolates have a discontinuous 131-amino-acid …
The Porcine Reproductive and Respiratory Syndrome Virus nsp2 …
The N terminus of the replicase nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome virus (PRRSV) contains a putative cysteine protease domain (PL2).
The full-length nsp2 replicase contributes to viral assembly in …
2024年11月27日 · This study reveals a novel role for nonstructural protein 2 (nsp2) in highly pathogenic porcine reproductive and respiratory syndrome virus type 2 (HP-PRRSV-2), …
Nonstructural proteins nsp2TF and nsp2N of porcine ... - PubMed
Recently, we identified a unique -2/-1 ribosomal frameshift mechanism in PRRSV, which yields two truncated forms of nonstructural protein (nsp) 2 variants, nsp2TF and nsp2N. Here, in vitro …
NSP2 Is Important for Highly Pathogenic Porcine Reproductive …
2021年4月29日 · Prostaglandin E2 (PGE2) derived from arachidonic acid through the activation of the rate-limiting enzyme cyclooxygenase type 1/2 (COX-1/2) plays an important role in fever. …
PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ …
2025年1月27日 · Our findings uncover a novel function of PRRSV-2 nsp2 in the activation of inflammatory responses, advancing our understanding of PRRSV-2 pathogenesis, and …
Research Progress of Porcine Reproductive and Respiratory …
In this paper, we review the structural composition, programmed ribosomal frameshift and biological properties of NSP2 to facilitate basic research on PRRSV and to provide theoretical …
猪繁殖与呼吸综合征病毒NSP2蛋白研究进展,Viruses - X-MOL
本文对NSP2的结构组成、程序化核糖体移码和生物学特性进行综述，以期促进PRRSV的基础研究，为疾病预防控制和治疗药物开发提供理论支持。 Porcine reproductive and respiratory …