2017年6月13日 · We show that Drosophila Efa6 (also known as dPSD), a guanine exchange factor and activator of Arf6, is required for normal alcohol-induced behaviors.

An analysis of the human ortholog of Arf6 and orthologs of Efa6 (PSD1-4) revealed that the minor G allele of single nucleotide polymorphism (SNP) rs13265422 in PSD3, as well as a haplotype containing rs13265422, was associated with an increased frequency of drinking and binge drinking episodes in adolescents.

analysis of the human ortholog of Arf6 and orthologs of Efa6 (PSD1-4) revealed that the minor G allele of single nucleotide polymorphism (SNP) rs13265422 in PSD3, as well as a haplotype...

2017年4月12日 · An analysis of the human ortholog of Arf6 and orthologs of Efa6 (PSD1-4) revealed that the minor G allele of single nucleotide polymorphism (SNP) rs13265422 in PSD3, as well as a haplotype containing rs13265422, was associated with an increased frequency of drinking and binge drinking episodes in adolescents.

对人类 Arf6 直系同源物和 Efa6 直系同源物 (PSD1-4) 的分析表明，PSD3 中单核苷酸多态性 (SNP) rs13265422 的次要 G 等位基因以及包含 rs13265422 的单倍型与饮酒频率增加有关和青少年暴饮暴食。

2017年6月13日 · The Arf6 activator Efa6/PSD3 was associated with ethanol-induced sedation and reduced tolerance development in drosophila and with altered prefrontal cortex activation during behavioral...

2017年12月14日 · PSD3 acts as an ARF6 GEF by localizing at the plasma membrane, which is mediated by its PH domain and stabilized by its CC domain. Alternative splicing of the PSD3 gene has been described in...

As predicted, Psd3-ASO downregulates the expression of PSD3 in mice induced by a NASH diet, and decreases the expression of the lipogenic enzymes acetyl-CoA carboxylase (ACC), fatty acid...

Pleckstrin 和 sec7 结构域包含 3 (PSD3)，也称为 EFA6R，已被证明与一些癌症相关，如急性髓性白血病、乳腺癌转移和星形细胞瘤。 但PSD3是否发挥作用以及如何在甲状腺癌中发挥作用尚不清楚。 /n方法：通过查阅以往的文献推测PSD3可能在甲状腺癌中发挥重要作用。

We show that Drosophila Efa6 (also known as dPSD), a guanine exchange factor (GEF) and activator of Arf6, is required for normal alcohol-induced behaviors.