
Progressive Supranuclear Palsy (PSP) - National Institute of ...
2025年3月12日 · Progressive supranuclear palsy (PSP) is a rare neurological disorder that affects body movements, walking and balance, and eye movements. PSP is caused by damage to …
Cross species systems biology discovers glial - Nature
2023年11月2日 · Progressive supranuclear palsy (PSP) is a neurodegenerative parkinsonian disorder characterized by cell-type-specific tau lesions in neurons and glia. Prior work...
Cross-disorder and disease-specific pathways in dementia ... - Cell …
2024年9月11日 · We performed single-nuclear RNA-seq and ATAC-seq in Alzheimer’s disease (AD), frontotemporal dementia (FTD), and progressive supranuclear palsy (PSP), analyzing 41 …
Genetic, transcriptomic, histological, and biochemical analysis of ...
2024年9月9日 · Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from …
Progressive Supranuclear Palsy: Pathology and Genetics - PMC
Progressive supranuclear palsy (PSP) is an atypical Parkinsonian disorder associated with progressive axial rigidity, vertical gaze palsy, dysarthria and dysphagia that was first described …
Autologous mesenchymal stem cell therapy for progressive …
Autologous bone marrow (BM) mesenchymal stem cells (MSC) from patients affected by different type of parkinsonisms have shown their ability to improve the dopaminergic function in …
Single-cell atlas of progressive supranuclear palsy reveals a
2021年4月12日 · Progressive supranuclear palsy (PSP) is a neurodegenerative disorder whose molecular complexity at a single cell level has not been evaluated. Here we analyzed 45,559 …
2023年11月17日 · RNA sequencing and analyzed 45,559 high quality nuclei targeting the subthalamic nucleus and adjacent structures from human post-mortem PSP brains with …
discover, replicate, and annotate thousands of differentially expressed genes in PSP, many of which reside in glia-enriched co-expression modules and cells. We prioritize DDR2, STOM, …
Treatment of progressive supranuclear palsy with autologous …
2014年3月4日 · Progressive supranuclear palsy is a relentlessly progressive neurodegenerative disorder and is clinically characterized by parkinsonism. Adipose tissue-derived mesenchymal …