2024年6月3日 · Propylthiouracil (PTU) works by blocking the production of the thyroid hormones thyroxine (T4) and triiodothyronine (T3) in the thyroid gland. It does this by interfering with the thyroid peroxidase enzyme, which normally aids in the incorporation of iodine into the thyroglobulin protein to form the thyroid hormones.

2023年6月5日 · Propylthiouracil is an anti-thyroid drug used to manage Graves disease and hyperthyroidism. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) of propylthiouracil pertinent for healthcare team members in the ...

PROPYLTHIOURACIL (PTU) (proe pill thye oh YOOR a sill) lowers the amount of thyroid hormone made by the thyroid gland. It treats hyperthyroidism (where the thyroid gland makes too much hormone). It also is used before thyroid surgery or radioactive iodine treatment.

Propylthiouracil (PTU) is a medication used to treat hyperthyroidism. [3] This includes hyperthyroidism due to Graves' disease and toxic multinodular goiter. [3] In a thyrotoxic crisis it is generally more effective than methimazole. [3] Otherwise it is typically only used when methimazole, surgery, and radioactive iodine is not possible. [3]

Propylthiouracil (PTU) is a prescription medication used to manage hyperthyroidism and Graves' disease. The most common side effects of PTU include rash, itching, hives, abnormal hair loss, and skin pigmentation. Since methimazole is associated with fetal abnormalities, PTU is used during the first trimester if an antithyroid drug is needed.

2025年2月1日 · Propylthiouracil is used to treat Graves' disease and hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It is also used before thyroid surgery or radioactive iodine treatment in patients who have already been treated with other medicines (e.g., methimazole) that did not work well.

Propylthiouracil is commonly used to treat people with Graves' disease or toxic multinodular goiter who have an overactive thyroid (hyperthyroidism). Propylthiouracil can also be used to help...

2024年6月16日 · Learn about the side effects of propylthiouracil, from common to rare, for consumers and healthcare professionals.

Propylthiouracil is a thiourea antithyroid agent. Grave's disease is the most common cause of hyperthyroidism. It is an autoimmune disease where an individual's own antibodies attach to thyroid stimulating hormone receptors within cells of the thyroid gland and then trigger overproduction of thyroid hormone.

2024年11月18日 · Propylthiouracil may be the treatment of choice when an antithyroid drug is indicated during or just prior to the first trimester of pregnancy because of the risk of fetal abnormalities associated with methimazole. (See Fetal/Neonatal Morbidity and also see Pregnancy under Cautions.) Antithyroid agent; thiourea-derivative.