PROZINC ® (protamine zinc recombinant human insulin) is a sterile aqueous solution of protamine zinc recombinant human insulin that is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus.

ProZinc®is the first and only FDA-approved insulin for cats made from recombinant DNA (DNA molecules created from the DNA of two unrelated organisms) that is identical to human insulin. The ingredients in ProZinc ® (protamine zinc insulin) are classified as long-acting with duration of effect for 10-14 hours.

PROZINC ® (protamine zinc recombinant human insulin) treatment for diabetes mellitus is the only FDA-approved veterinary insulin made with recombinant technology. It’s the only product scientifically formulated with protamine zinc to support optimal glycemic control and extended duration of action. Read on to learn more about PROZINC insulin.

2019年5月10日 · Most cats are well regulated on insulin at an average dose of 0.5 U/kg q 12 hr, with a range of 0.2–0.8 U/kg. OR PZI (ProZinc) , at a typical starting dose of 1–2 U per cat q 12 hr

2019年5月10日 · PZI (U-40 human recombinant protamine zinc insulin; ProZinc, Boehringer Ingelheim Animal Health) is considered by clinicians as a long-acting insulin, and is FDA approved for use in cats and dogs.

Recently, a recombinant human PZI insulin licensed for use in cats (ProZinc®) has been released in the US; most likely, it will become available in other countries in the near future. A preliminary study showed that good glycemic control was achieved in a substantial percentage of cats.

There are currently four insulins commonly in use for cats: Vetsulin (also marketed as Caninsulin® in other countries), PZI insulin (currently available as Prozinc® insulin), Lantus® insulin (also called Glargine® or Basaglar®), and Humulin (genetically engineered human insulin available in several formulations with different durations of ...

Healthy cats are able to regulate their blood glucose levels with the help of insulin that’s produced in the body. Cats with diabetes have a harder time maintaining those levels throughout the day, due to an ineffective response to insulin or an insulin deficiency. That’s where PROZINC® comes in.

BCP Veterinary Pharmacy has replicated the discontinued formula for 100% bovine protamine zinc insulin (PZI). With only one amino acid difference occurring at site A18, bovine PZI is the closest match to feline insulin available. Cats can accept this insulin better because it is much more like their own.

The current PZI preparation (ProZinc®) is a recombinant human insulin formulation that has been shown to be effective in controlling glycemia and inducing diabetic remission in cats. The most common problem with ProZinc® is a prolonged duration of effect (greater than 12 hours), which can create issues with hypoglycemia and the Somogyi ...