There is a distinct relationship between PaO2 and SpO2 which is illustrated by the Oxygen Dissociation Curve (see image). This relationship can be altered by many factors (e.g. temperature, FDG, pH) but generally follows the classic “S-shape” graph with PaO2 on the x axis and oxygen saturation on the y axis.

The understanding of sigmoidal-shaped oxy–Hb dissociation curve comes very handy in these situations [Figure 1]. O 2 saturation varies with the PaO 2 in a nonlinear relationship and is affected by temperature, pH, 2,3 diphosphoglycerate, and PaCO 2 (partial pressure of carbon dioxide in the arterial blood). [3]

In clinical practice, the level of arterial oxygenation can be measured either directly by blood gas sampling to measure partial pressure (PaO2) and percentage saturation (SaO2) or indirectly by pulse oximetry (SpO2). This review addresses the strengths and weaknesses of each of these tests and gives advice on their clinical use.

The Oxyhemoglobin Dissociation curve shows how blood carries oxygen through the body. It also shows the relationship between SpO2 and PaO2 as determined by hemoglobin's affinity for oxygen. Here is a simple way of understanding the curve. Fick's law: According to this law, a gas travels from areas of high pressure to areas of low pressure.

2019年9月22日 · The Oxygen-Hemoglobin Dissociation Curve shows the percent of oxygen binding to Hgb per mmHg. An O2 sat of 90% corresponds to a PaO2 of 60 mmHg. Note how quickly Hgb loses oxygen below 90% saturation.

2012年2月22日 · Users can adjust R (respiratory quotient), PACO2 (alveolar partial pressure of carbon dioxide), Patm (barometric pressure), FiO2 (fraction of inspired oxygen), and PaO2 (a …

2016年6月7日 · The oxygen dissociation curve is a graph that plots the proportion of haemoglobin in its oxygen-laden saturated form on the vertical axis against the partial pressure of oxygen on the horizontal axis.

The oxygen-hemoglobin disassociation curve is a graph that shows the relationship between the partial pressure of oxygen (PaO2) in mmHg and the percentage of oxygen saturation.

There is a distinct relationship between PaO2 and SpO2 which is illustrated by the Oxygen Dissociation Curve (see image). This relationship can be altered by many factors (e.g. temperature, FDG, pH) but generally follows the classic “S-shape” graph with PaO2 on the x axis and oxygen saturation on the y axis.

2024年10月31日 · At low pO2, in the bottom left corner of the graph, oxygen binds slowly to haemoglobin; this means that haemoglobin cannot pick up oxygen and become saturated as blood passes through the body's oxygen-depleted tissues