2023年3月23日 · The model suggests the conditions under which a CA1 microcircuit can operate to elicit theta-gamma PAC, and highlights the modulatory role of OLM and PVBC cells, recurrent connectivity, and short term synaptic plasticity.

海马PAC-电极表现出theta-gamma耦合，更有可能诱发突触联结的长期抑制;然而，有趣的是，“皮质”慢theta波振荡的首选相位与这些海马PAC电极之间的相位差与我们之前描述的海马和颞叶皮层之间慢theta波频率振荡同步的相位偏移相似。

2023年3月23日 · The model suggests the conditions under which a CA1 microcircuit can operate to elicit theta-gamma PAC, and highlights the modulatory role of OLM and PVBC cells, recurrent connectivity, and short term synaptic plasticity.

2011年3月1日 · Models have attempted to link hippocampal theta–gamma PAC with CA1-dependent memory processing, whereby subsets of hippocampal units co-active during individual gamma cycles are recruited in consistent, sequential order dependent upon theta cycle phase (Lisman and Buzsaki, 2008, Lisman and Idiart, 1995; see also Fuentemilla et al., 2010).

2024年6月7日 · 本研究旨在探索海马CA3区θ~γ神经振荡相位-幅值耦合 (phase-amplitude coupling, PAC)强度与大鼠电击回避训练前后空间辨别和认知能力改变的相关性。 依据Y型迷宫电击回避训练结果，将CA3区埋置电极大鼠分为快回避反应组和普通回避反应组。 无线遥测电击回避训练前后两组大鼠海马CA3区神经元局部场电位 (local field potential, LFP)，利用MATLAB小波包提取分析CA3区θ振荡 (3~7 Hz)与低频γ振荡 (30~60 Hz) PAC变化。 结果显示，快回避反应组大鼠在训 …

2019年5月6日 · In this work, we introduce a new application of PAC to two LFPs and suggest that it can be used to infer the direction and strength of rhythmic neural transmission between distinct brain networks.

2024年7月16日 · PAC (phase-amplitude coupling) was calculated on 1 to 100 Hz filtered CA1 LFP signal with the PAC toolbox (Yang et al., 2021). The range of phase vector was set as 1–30 Hz, and the range of amplitude vector was set as 30–100 Hz (Figure 5B).

结论 1.VD大鼠CA3theta-CA1gamma的PAC下降的原因在于CA3theta与CAlgamma幅值之间相位耦合的改变. 2.在VD大鼠中,CA3, CA1在theta, gamma节律内,节律间的协调能力下降,可能是VD大鼠认知受损的神经网络机制. 3.基于场电位的神经信息流指标 (gPDC, PAC_CMI)或许可以用来反映CA3-CA1通路的 ...

PAC between CA1 theta and slowgamma oscillations in Cacna1c +/− rats was reduced specifically during exploration of a novel environment, indicating a mis-coupling between CA1 neurons and ...

为了检验近期回忆期间γ活动的增加是否与theta -γ耦合的改变有关，计算了近期和远期记忆回忆期间BLA中局部场电位的PAC。 通过调制指数来量化的PAC强度，在非僵直期的theta相位和慢γ幅度之间是最大的，这表明在这些时段内，theta到慢γ的耦合占主导地位。