Angle closure refers to a diverse group of anatomical disruptions of the anterior segment that lead to mechanical blockage of the trabecular meshwork by the peripheral iris, thereby resulting in increased IOP with subsequent optic disc and visual field changes that together diagnostically is referred to as angle-closure glaucoma.

原发性闭角型青光眼（primary angle closure glaucoma，PACG）是由原发性房角关闭所导致的急性或慢性眼压升高，造成视盘改变和视野损伤的一组疾病。 近年关于PACG的研究取得了新的进展，为此中华医学会眼科学分会青光眼学组以眼科循证医学为基础，经过充分讨论，对我国PACG的分类体系和诊断方法以及治疗原则达成进一步共识性意见，以供临床医师在对青光眼进行诊断和治疗时参考使用。 近年针对PACG的研究取得了新的进展。 研究发现PACG的发生和发展与虹 …

2017年3月1日 · Angle closure is the primary fundamental problem in PACG, while elevated intraocular pressure (IOP) is secondary to angle closure. To some extent, PACG is a preventable disease if the angle closure process can be halted in the early stages.

Primary angle closure glaucoma (PACG) is a chronic optic neuropathy associated with a loss of retinal ganglion cells and their axons. Pupil block is the most common cause. Patients with angle closure disease are typically asymptomatic until the condition becomes more advanced.

Primary angle-closure glaucoma (PACG) is a common cause of blindness. Angle closure is a fundamental pathologic process in PAGC. With the development of imaging devices for the anterior segment of the eye, a better understanding of the pathogenesis of …

2013年12月18日 · Angle-closure glaucoma (ACG) is a group of diseases in which there is reversible (appositional) or adhesional (synechial) closure of the anterior-chamber angle. The angle closure may occur in an acute or chronic form.

2017年10月28日 · The researchers assessed the efficacy, safety, and cost-effectiveness of clear lens extraction versus laser peripheral iridotomy for the first-line treatment of PACG and PAC. Inclusion criteria for patients were: age 50 years or older, absence of cataract, and mild or moderate PACG or newly diagnosed PAC with IOP of 30 mm Hg or greater.

Primary angle-closure glaucoma is potentially a devastating disease, responsible for half of glaucoma-related blindness worldwide. Angle closure is characterized by appositional approximation or contact between the iris and trabecular meshwork. It tends to develop in eyes with shallow anterior chamb …

2015年7月24日 · Primary Angle Closure Glaucoma (PACG) is one of the most common types of glaucoma affecting over 15 million individuals worldwide. Family history and...

2023年1月1日 · Primary angle-closure glaucoma (PACG) is a leading cause of blindness worldwide and its prevalence is projected to increase by 20% per decade due to greater life expectancy. However, most patients with PACG remain undiagnosed. The disease includes a wide clinical spectrum of presentations with varied mechanisms.