Primary angle-closure glaucoma (PACG) is a progressive optic nerve degeneration and is defined as a glaucomatous optic neuropathy with associated characteristic enlargement of optic disc cupping and visual field loss that is secondary to ocular hypertension caused by closure of …

2017年3月1日 · Primary angle-closure glaucoma (PACG) is a common cause of blindness. Angle closure is a fundamental pathologic process in PAGC. With the development of imaging devices for the anterior segment of the eye, a better understanding of the pathogenesis of angle closure has been reached.

Primary angle closure glaucoma (PACG) is a chronic optic neuropathy associated with a loss of retinal ganglion cells and their axons. Pupil block is the most common cause. Patients with angle closure disease are typically asymptomatic until the condition becomes more advanced.

2025年2月7日 · Primary angle closure disease (PACD) is a spectrum that commences with primary angle-closure suspect (PACS), which in a subset of patients, can result in the...

2021年6月18日 · The aim of this study was to investigate the optic disc morphology in primary angle-closure glaucoma (PACG) versus primary open-angle glaucoma (POAG) in South Indians.

2024年12月1日 · Purpose: To assess the microvasculature in the optic nerve head (ONH) and macula across the primary angle closure disease (PACD) spectrum using optical coherence tomography angiography (OCTA). Materials and methods: OCTA (AngioVue, Fremont, CA) imaging was performed on 122 PACD subjects.

Angle closure refers to a diverse group of anatomical disruptions of the anterior segment that lead to mechanical blockage of the trabecular meshwork by the peripheral iris, thereby resulting in increased IOP with subsequent optic disc and visual field changes that together diagnostically is referred to as angle-closure glaucoma.

2024年9月16日 · This review synthesizes the similarities and differences in the etiology of optic neuropathy caused by POAG and PACG, considering their respective pathophysiological mechanisms, the morphology of the optic disc and surrounding tissues, genetic characteristics, optical coherence tomography angiography, optical coherence tomography, and ...

2023年7月15日 · PACG is characterized by glaucomatous visual damage. In the early phases of PACG, like the preclinical or intermittent stages, or primary angle closure, optic nerve damage is undetectable [9]. It is well known that typical structural damage in …

PRIMARY ANGLE-CLOSURE GLAUCOMA (PACG), ESPEcially acute PACG, is a significant cause of blindness. 1 It is estimated that the number of people with PACG worldwide will increase to 23.4 million in 2020, 76.7% of whom will be Asian. 2 PACG accounted for bilateral irreversible blindness in 3.9 million people in 2010, and this number is predicted ...