HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300 ...
Here, we describe an essential role for HLA-B-associated transcript 3 (Bat3)/Scythe in controlling the acetylation of p53 required for DNA damage responses. Depletion of Bat3 from human and …
Sci Immunol丨Tim-3 适配器蛋白 Bat3 是耐受性树突状细胞 - 知乎
2023年11月1日 · 文章主要研究了Tim-3和其适配蛋白Bat3在调节免疫应答中的作用。 研究发现，Bat3作为Tim-3的适配蛋白，在调节树突状细胞（DCs）功能中起到关键作用。 在小鼠的自 …
HLA-B associated transcript 3 - Wikipedia
Large proline-rich protein BAT3 is a protein that in humans is encoded by the BAT3 gene. [5] [6] A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha …
HLA-B-associated transcript 3 (Bat3/Scythe) negatively ... - Nature
2011年12月1日 · Here, we describe the regulation of bone morphogenic protein (BMP) signaling by Bat3 (also known as Scythe or BAG6). Bat3 overexpression in murine cell lines suppresses …
BAT3 modulates p300-dependent acetylation of p53 and autophagy ... - PNAS
2014年3月3日 · Here we report a unique regulator of autophagy, BAT3, which modulates the intracellular localization of the enzyme p300, an enzyme that adds some acetyl residues on …
HLA-B 关联转录因子3 在免疫相关疾病中的作用 - 豆丁网
2015年9月14日 · 临床实验都表明, BAT3可以抵抗Gal-9/Tim-3. 的抑制作用, 促进Th1介导的各种炎症反应. BAT3与Ti m-3的相互作用有望成为多种自身. 免疫性和炎症性疾病的治疗靶点. 此外, …
Furthermore, consistent with our in vitro findings, thymocytes from Bat3-deficient mice exhibit reduced induction of puma and p21, and are resistant to DNA damage-induced apoptosis in …
HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300 ...
2007年4月1日 · Here, we describe an essential role for HLA-B-associated transcript 3 (Bat3)/Scythe in controlling the acetylation of p53 required for DNA damage responses. …
HLA-B-associated transcript 3 (Bat3) stabilizes and activates ... - PubMed
2020年2月20日 · Here, we identified a novel HAUSP-interacting protein, HLA-B-associated transcript 3 (Bat3) and found it to be capable of inducing p53 stabilization and activation via a …
Bat3 promotes T cell responses and autoimmunity by repressing …
2012年8月5日 · Here we show that human leukocyte antigen B (HLA-B)-associated transcript 3 (Bat3) binds to, and represses the function of, Tim-3. Bat3 protects T helper type 1 (T H 1) …