Permanent CIA (pCIA) is diagnosed when there is no hair regrowth or incomplete hair regrowth 6 months after chemotherapy cessation. The incidence of pCIA is dose- and schedule-related and has been associated with docetaxel given at doses of 75 mg/m 2 or higher per cycle, and less commonly paclitaxel [ 11 , 12 , 13 , 14 ].

In our study, we defined incomplete hair regrowth (PCIA) if hair density or thickness at 6 months were two standard deviations (SDs) or more below the baseline mean (before chemotherapy). Body image was measured using four questions from the validated Korean version of the European Organization for Research and Treatment of Cancer, Breast ...

Persistent chemotherapy-induced alopecia (PCIA) is defined as the absence of hair regrowth after more than 6 months of treatment discontinuation . Topical minoxidil has been considered as the drug of choice in prevention or treatment of CIA. In a case of PCIA the efficacy of topical minoxidil may be limited [2,3]. Moreover, it may cause scalp ...

2024年10月14日 · Compared to other chemotherapies, taxane-based treatments like docetaxel are associated with an 8-fold greater risk of inducing pCIA, where hair does not fully regrow within 6 months of stopping treatment

Persistent chemotherapy-induced alopecia, or PCIA, is hair loss that continues for more than six months after chemotherapy treatment ends, and in some cases, it can be permanent 1.

2024年9月1日 · Of 120 patients treated with scalp cooling caps during chemotherapy administration, only 1 patient developed pCIA. Treatment with 1 mg daily oral minoxidil led to cosmetically significant hair growth within 6 wk. Short hair regrowth was predominantly located in the frontal and parietal areas.

2023年4月1日 · In this study, we report successful treatment of a patient suffering from persistent chemotherapy-induced alopecia (PCIA) with extracellular enriched vesicles (EVs) derived from human placental mesenchymal stromal cells (MSCs).

2022年4月1日 · Permanent chemotherapy-induced alopecia (pCIA) is the absence of hair regrowth after more than 6 months of treatment discontinuation. 1 pCIA has a profound impact on patients’ quality of life. 1 Data on the pathophysiology and treatment of pCIA are scarce. 1 We describe a patient who developed pCIA after hematopoietic stem cell ...

2024年8月27日 · Persistent chemotherapy-induced alopecia (pCIA) is a condition where hair loss continues for an extended period (more than 6 months) after the completion of chemotherapy. Unlike temporary hair loss, which is a common side effect of chemotherapy that usually resolves within a few months after treatment ends, pCIA involves incomplete hair ...

2022年5月21日 · Many of the patients with a failure to regrow back their hair to the same density have a phenomenon known as persistent chemotherapy induced alopecia (PCIA). This is defined as a failure to experience full hair regrowth by month 6 …