丙酮酸脱氢酶 E1 亚基 β（PDHB）基因 | MCE
丙酮酸脱氢酶 (PDH) 复合物是一种核编码的线粒体多酶复合物，可催化丙酮酸向乙酰辅酶 A 和二氧化碳的整体转化，并提供糖酵解和三羧酸 (TCA) 循环之间的主要联系。 PDH 复合物由三种 …
PDHB Gene - GeneCards | ODPB Protein | ODPB Antibody
Dec 25, 2024 · PDHB (Pyruvate Dehydrogenase E1 Subunit Beta) is a Protein Coding gene. Diseases associated with PDHB include Pyruvate Dehydrogenase E1-Beta Deficiency and …
丙酮酸脱氢酶的结构、功能与相关疾病 - 知乎 - 知乎专栏
丙酮酸彻底氧化分解需要先转变为乙酰辅酶A，由 丙酮酸脱氢酶复合体 （pyruvate dehydrogenase complex，PDH或PDC）催化。 这个反应需要三种酶连续催化，依次称为E1（丙酮酸脱氢 …
Pyruvate dehydrogenase (lipoamide) beta - Wikipedia
Pyruvate dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in humans is encoded …
杏林简讯｜除了Warburg效应，三羧酸循环竟然也能促进癌细胞的生存与转移能力 …
丙酮酸位于糖酵解和TAC循环的交叉点，其代谢命运主要受 乳酸脱氢酶 （LDH）和 丙酮酸脱氢酶复合体 （PDHc） 调控。 前者通过将丙酮酸转化为乳酸来促进糖酵解，而后者通过将丙酮酸 …
异牛皮苷通过抑制pdhb介导的葡萄糖代谢重编程来缓解肝细胞癌 …
Feb 10, 2025 · 本研究证实 pdhb 是肝癌中具有预测肿瘤进展和索拉非尼耐药作用的癌基因。pdhb 通过结合糖酵解相关基因启动子促进转录，介导糖代谢重编程，进而促进肝癌细胞增殖、侵袭 …
PDHB pyruvate dehydrogenase E1 subunit beta [ (human)]
Gene ID: 5162, updated on 9-Feb-2025. The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of …
PDHB pyruvate dehydrogenase E1 subunit beta - NIH Genetic …
Feb 9, 2025 · The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and …
丙酮酸脱氢酶与肿瘤 - 仁和软件
丙酮酸脱氢酶（pyruvate dehydrogenase，PDH）， 是由丙酮酸脱氢酶 E1α亚单位（PDHA1）和E1β 亚单位（PDHB）基因编码的α和β亚基组成的结 合硫胺素焦磷酸盐（TPP）的异四聚体 。
PDHB gene - MedlinePlus
Mutations in the PDHB gene are a very rare cause of pyruvate dehydrogenase deficiency. This condition is characterized by a potentially life-threatening buildup of a chemical called lactic …