
PDHX Gene - GeneCards | ODPX Protein | ODPX Antibody
2024年12月25日 · PDHX (Pyruvate Dehydrogenase Complex Component X) is a Protein Coding gene. Diseases associated with PDHX include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and Pyruvate Dehydrogenase E1-Alpha Deficiency. Among its related pathways are Regulation of pyruvate metabolism and ESR-mediated signaling.
PDHX pyruvate dehydrogenase complex component X [ (human)]
This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood.
PDHX gene - MedlinePlus
The PDHX gene provides instructions for making a protein called E3 binding protein, which is part of a large group of proteins known as the pyruvate dehydrogenase complex. Learn about this gene and related health conditions.
PDHX acetylation facilitates tumor progression by disrupting PDC ...
2025年1月4日 · Here, we demonstrate that the acetylation of Lys 488 of pyruvate dehydrogenase complex component X (PDHX) commonly occurs in hepatocellular carcinoma, disrupting PDC assembly and contributing to lactate-driven epigenetic control of gene expression. PDHX, an E3-binding protein in the PDC, is acetylated by the p300 at Lys 488, impeding the ...
PDHX - pyruvate dehydrogenase complex component X Gene
This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood.
Entry - *608769 - PYRUVATE DEHYDROGENASE COMPLEX, COMPONENT X; PDHX …
The PDHX gene encodes component X of the pyruvate dehydrogenase (PDH) complex. For a detailed description of the pyruvate dehydrogenase complex, see 300502.
PDHX (human) | Gene Target - PubChem
2016年9月14日 · The PDHX gene provides instructions for making a protein called E3 binding protein, which is part of a large group of proteins known as the pyruvate dehydrogenase complex. This complex is made up of several enzymes, including one called E3, and other proteins.
PDHX gene information - The Human Protein Atlas
The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle.
Human Gene PDHX (ENST00000227868.9) from GENCODE V46
This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood.
PDHX pyruvate dehydrogenase complex component X [Homo …
2024年2月17日 · This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood.
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