2005年6月13日 · Pegademase is a modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.

2025年2月1日 · Pegademase contains an enzyme called adenosine deaminase (ADA). It is used to treat children who do not have a properly developed immune system because of a lack of ADA in the body. Pegademase is to be given only by or under the supervision of your doctor.

2023年4月25日 · ADAGEN® (pegademase bovine) Injection is indicated for enzyme replacement therapy for adenosine deaminase (ADA) deficiency in patients with severe combined immunodeficiency disease (SCID) who are not suitable candidates for – or who have failed – bone marrow transplantation.

Other therapeutic options include enzyme replacement therapy (ERT) with pegademase bovine (hereon referred to as PEG-ADA) and more recently, gene therapy. PEG-ADA was first used to treat ADA deficiency in 1986 and to date more than …

2024年6月17日 · ADAGEN ® (pegademase bovine) Injection is a modified enzyme used for enzyme replacement therapy for the treatment of severe combined immunodeficiency disease (SCID) associated with a deficiency of adenosine deaminase.

Pegademase In subject area: Pharmacology, Toxicology and Pharmaceutical Science Adagen is a PEG–adenosine deaminase molecule used to treat severe combined immunodeficiency (SCID), which is caused by a lack of the adenosine deaminase enzyme in the body (i.e., ADA-SCID).

2016年6月17日 · Pegademase contains an enzyme called adenosine deaminase (ADA). It is used to treat children who do not have a properly developed immune system because of a lack of ADA in the body. Pegademase is to be given only by or under the supervision of your doctor.

Adenosine deaminase deficiency (ADA) is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities.

Pegademase is a Enzyme that is FDA approved for the treatment of adenosine deaminase (ADA) deficiency in patients with severe combined immunodeficiency disease. Common adverse reactions include Injection site pain.

2024年4月10日 · Easy-to-read patient leaflet for Pegademase Bovine Injection. Includes indications, proper use, special instructions, precautions, and possible side effects.