2024年6月2日 · Based on the risk scores, PRAD patients were stratified into high-risk and low-risk cohorts. The Receiver operating characteristics (ROC) and Kaplan–Meier survival analyses corroborated the exceptional predictive performance of our novel risk model.

2024年9月17日 · ZNF330 and PITPNM are the eKDEGs for PRAD, which can be used as potential new prognostic markers. The two-factor combined risk model can effectively assess the survival and prognosis of PRAD patients, but also can predict the different responses of immunotherapy to PRAD patients, which …

转移是前列腺腺癌 （prad） 患者治疗失败的主要原因。 不同的程序性细胞死亡 （PCD） 模式在肿瘤转移中起重要作用，并有望成为 PRAD 转移的预测指标。

2019年1月28日 · Large-scale genomics studies have identified recurrently mutated genes in the ETS gene family, including fusions and copy number variations (CNVs), which are involved in the development of prostate adenocarcinoma (PRAD). However, the aetiology of …

2020年5月18日 · 背景前列腺腺癌（prad）是老年男性常见的恶性肿瘤。我们的研究使用癌症基因图谱 (tcga) 数据库来寻找潜在的相关基因来预测 prad 患者的预后。方法 我们从 tcga 下载了 490 名 prad 患者（患者年龄：41-78 岁）的基因表达谱和临床样本信息。

2021年8月11日 · 作者先分析了498名原发前列腺癌患者的tcga prad rna-seq数据，并进行了如下两个方向的探索： （1）比较低STAT3和高STAT3患者的差异基因。 共发现有1194个显著差异基因(FC ≥ 2，FDR ≤ 0.05)。

2024年9月16日 · Prostate adenocarcinoma (PRAD) is a prevalent global malignancy which depends more on lipid metabolism for tumor progression compared to other cancer types. Although Stearoyl-coenzyme A desaturase (SCD) is documented to regulate lipid metabolism in multiple cancers, landscape analysis of its implica …

2023年8月12日 · The integrated nomogram can be a good predictor of 3- and 5-year survival in patients with PRAD. This risk model is valuable for guiding the selection of immunotherapy and chemotherapy in the clinical treatment of patients with PRAD.

2018年11月1日 · Prostate adenocarcinoma (PRAD) is the most common cancer in men. The aim of this study was to reveal the critical long non-coding RNA (lncRNAs), microRNA (miRNAs) and mRNAs involved in the pathogenesis of PRAD.

2020年7月31日 · BACKGROUND Prostate adenocarcinoma (PRAD) is the second most common malignancy in males and the fifth leading cause of cancer mortality. Cancer stem cells (CSCs) play an important role in the occurrence and development of PRAD, however, the prognostic biomarkers associated with CSC features have not …