PH-20 is a sperm plasma-membrane protein that has been shown to have hyaluronidase activity in several mammalian species including nonhuman primates. In this investigation, the PH-20 protein was characterized in noncapacitated human sperm and in capacitated human sperm.

PH-20 is a specific type of hyaluronidase that plays a critical role in the fertilization process by facilitating the initial binding of sperm to the glycoprotein layer surrounding the oocyte and subsequently breaking down hyaluronic acid polymers in …

2001年12月1日 · The neutral enzyme activity of plasma membrane PH-20 is responsible for local degradation of the cumulus ECM during sperm penetration. Plasma membrane PH-20 mediates HA-induced sperm signaling via a HA binding domain that …

Human hyaluronidase PH20 (hPH20), a glycosylphosphatidylinositol (GPI)-anchored membrane protein in mammalian sperm, is a widely recognized hyaluronidase (Cherr et al., 2001). hPH20 could effectively hydrolyze the HA-rich matrix of the oocyte to …

请看这个答案，pH适合用来度量稀酸稀碱。 浓度过大的强酸强碱中的酸性和碱性离子已经不是氢氧根和水合质子了，那样的pH可以称为表观pH 发布于 2021-03-19 10:53

2022年5月12日 · Human hyaluronidase PH20 (hPH20), a glycosylphosphatidylinositol (GPI)-anchored membrane protein in mammalian sperm, is a widely recognized hyaluronidase (Cherr et al., 2001). hPH20 could effectively hydrolyze the HA-rich matrix of the oocyte to facilitate the penetration of the sperm.

Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation.

pH的范围为0~14，仅适用于稀溶液。 对于氢离子或氢氧根离子浓度较大（超过1 mol/L）的溶液，其酸碱度直接用相应的浓度来表示。 酸碱度是水溶液的一项重要指标，工农业生产、科学实验以及人们的生活和健康都与溶液的酸碱度具有密切关系。 显然，在 纯水 中，两种电离产物H3O + 和OH - 的浓度应相等，故为中性。 某些物质溶解在水中，会导致水中H + 的浓度大于OH -。 例如氯化氢气体溶于水后会电离出大量的H + 和Cl -，使得H + 浓度增大，而且水的电离平衡逆向移 …

2013年1月2日 · ABSTRACT: PH-20 is a sperm plasma-membrane protein that has been shown to have hyaluronidase activity in several mammalian species including nonhuman primates. In this investigation, the PH-20 protein was characterized in noncapacitated human sperm and in capacitated human sperm.

Hyaluronidases are a group of glycosidases catalyzing the degradation of hyaluronic acid (HA). Because of the advantages of effectively hydrolyzing the HA-rich matrix and low immunogenicity, human...