
PhKv a toxin isolated from the spider venom induces ... - PubMed
PhKv is a peptide isolated from the venom of the armed spider Phoneutria nigriventer. It has an antiarrythmogenic activity that involves the enhanced release of acetylcholine. The aim of this …
PhKv a toxin isolated from the spider venom induces …
2017年10月1日 · PhKv, a peptide from P. nigriventer spider venom, does not affect thermal or mechanical sensitivity in mice. PhKv caused antinociception in the chronic constriction injury …
Antiarrhythmogenic effects of a neurotoxin from the spider
2011年2月1日 · In this study, we evaluated the effects of PhKv, a 4584 Da peptide isolated from the spider Phoneutria nigriventer venom, in the isolated rat heart and in isolated ventricular …
Assessment of the potential neuroprotective effect of PhKv toxin ...
2025年1月9日 · This study explores the therapeutic potential of PhKv toxin, derived from the Brazilian wandering spider Phoneutria nigriventer, as an acetylcholinesterase inhibitor, aiming …
Antiarrhythmogenic effects of a neurotoxin from the spider …
In this study, we evaluated the effects of PhKv, a 4584 Da peptide isolated from the spider Phoneutria nigriventer venom, in the isolated rat heart and in isolated ventricular myocytes. …
PhKv 是一种从蜘蛛毒液中分离出来的毒素,通过抑制胆碱酯酶激 …
PhKv 是从武装蜘蛛的毒液中分离出来的肽黑风鳅。 它具有抗心律失常活性,涉及增强乙酰胆碱的释放。 本研究的目的是调查 PhKv 是否对小鼠具有镇痛作用。
Drug Development - PubMed
This study explores the therapeutic potential of PhKv toxin, derived from the Brazilian wandering spider Phoneutria nigriventer, as an acetylcholinesterase inhibitor, aiming to prolong …
Spider-Venom Peptides: Structure, Bioactivity, Strategy, and …
The Phoneutria nigriventer peptide PhKv has shown a remarkable ability to rescue long-term memory in a mouse model of Alzheimer’s disease, due to its selective modulation of A-type …
Conclusion: PhKv shows promise in memory improvement, warranting in-depth investigations into its mechanisms. Ongoing research explores the molecular aspects of PhKv’s action on …
Neuroactive venom compounds obtained from Phlogiellus …
Spider venom is a rich cocktail of neuroactive compounds designed to prey capture and defense against predators that act on neuronal membrane proteins, in particular, acetylcholinesterases …
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