磷酸烯醇 丙酮酸 （英语：Phosphoenolpyruvate或Phosphoenolpyruvic acid；缩写PEP）是 生物细胞 中的常见生化分子，是糖解作用与糖质新生作用的 中间产物。 在糖解作用中，此分子是 2-磷酸甘油酸 在 烯醇化酶 （enolase）的催化下生成，是一个高能 磷酸 分子。 接下来磷酸烯醇 丙酮酸 将会进入糖解作用的第10个，也是最后一个步骤中。 在糖解作用的最后步骤里，磷酸烯醇丙酮酸将会经由 丙酮酸激酶 （Pyruvate kinase）的催化，使原本接在 氧原子 上的 磷酸根 转移到ADP …

之後草醋酸又會經由磷酸烯醇丙酮酸羧化激酶（Phosphoenolpyruvate carboxykinase）的催化，生成磷酸烯醇丙酮酸，在這個反應中，會消耗掉GTP，並生成GDP與二氧化碳。

Phosphoenolpyruvate (2-phosphoenolpyruvate, PEP) is the carboxylic acid derived from the enol of pyruvate and phosphate. It exists as an anion. PEP is an important intermediate in biochemistry. It has the highest-energy phosphate bond found (−61.9 kJ/mol) in organisms, and is involved in glycolysis and gluconeogenesis.

Phosphoenolpyruvic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Phosphoenolpyruvate has been reported in Drosophila melanogaster, Medicago sativa, and other organisms with data available. View More... C3H5O6P.

2025年1月4日 · Phosphoenolpyruvate (PEP) plays a key role in the development of plants and exists in a wide variety of species. Research on the metabolic activities of PEP in plants has received increasing attention. PEP regulates multiple processes in plant growth and development.

Phosphoenolpyruvate (PEP) is a highly functionalized, chemically versatile molecule that is used in several key biochemical steps in cellular energy metabolism and biosynthesis. 96 Although most enzymatic reactions utilizing PEP as a substrate involve cleavage of the high-energy P–O bond (ΔG°′ = −14.8 k cal mol −1), two types of ...

2022年12月1日 · Phosphoenolpyruvate is converted into either malate to fuel atmospheric nitrogen fixation in bacteroids or pyruvate for adenosine triphosphate (ATP) production in mitochondria for nitrogen assimilation and other cellular activities (fig. S1), and its allocation likely regulates nodule nitrogen fixation capacity (4–10).

2023年9月4日 · Mechanistically, the ENO2-derived metabolite phosphoenolpyruvate (PEP) selectively inhibits histone deacetylase 1 (HDAC1) activity, which increases the acetylation of β-catenin and activates the...

Pyruvate kinase (PK) catalyzes the dephosphorylation of phosphoenolpyruvate into pyruvate during the final, irreversible step of glycolysis. The breakdown of glucose via glycolysis yields two molecules of pyruvate and two net molecules of ATP. Thus, glycolysis is an important source of energy for most cells in the body.

2025年1月11日 · Explore the critical role and regulation of phosphoenolpyruvate in glycolysis and its impact on metabolic pathways. Phosphoenolpyruvate (PEP) is an intermediate in glycolysis, playing a role in energy production within cells. Its involvement in various biochemical reactions is vital for cellular respiration and energy balance.