2025年1月3日 · Persistent hyperplastic primary vitreous (PHPV), also known as persistent hyperplastic tunica vasculosa lentis (PHTVL) or PHPV/PHTVL, is a condition of the vitreous in which the ophthalmic embryologic vascular structures do not regress normally. 1,2 Because the normal embryologic vitreal vasculature is intimately associated with the posterior ...

Synonym (s): PHPV, Persistent hyperplastic tunica vasculosa lentis (PHTVL), PHTVL/PHPV. Cause: developmental ocular disorder. Signs: there is a spectrum of effects, from no visible outward signs to intraocular hemorrhage, cataracts and blindness. Diagnosis: ophthalmoscopy, ocular ultrasonography.

The most frequent clinical sign in dogs with PHPV was asymptomatic persistently increased liver enzymes (57.1%). Toy poodles were at a significantly higher risk of PHPV than other breeds among dogs that underwent liver biopsy (P < 0.001). The median survival time of dogs with PHPV was more than 5 years.

PHPV/PTVL stands for Persistent Hyperplastic Primary Vitreous/Persistent Tunica Vasculosa Lentis. PHPV is a congenital defect, meaning it is present at birth. It is due to abnormalities in the development and regression of the hyaloid artery.

What is PHPV? PHPV is a developmental abnormality of the eye which occurs in the puppy embryo at about 4-5 weeks of age after conception. Blood vessels which help develop the lens of the eye are not reabsorbed as they should be.

The objective of this study was to describe the clinical, histologic and immunohistochemical features, the surgical treatment, and outcome of a cataract secondary to persistent hyperplastic tunica vasculosa lentis/persistent hyperplastic primary vitreous (PHTVL/PHPV) in a dog. A 4-month-old male Blo …

2015年10月16日 · Unilateral persistent hyperplastic tunica vasculosa lentis/persistent hyperplastic primary vitreous (PHTVL/PHPV) in a German shepherd dog. Brief Communication; Published: 16 October 2015; Volume 25, pages 487–489, (2016) Cite this article

2017年12月21日 · Among the 48 canine cases, 28 dogs (58.3%) were diagnosed with PHPV, which was the most common diagnosis. The most frequent clinical sign in dogs with PHPV was asymptomatic persistently increased liver enzymes (57.1%). Toy poodles were at a significantly higher risk of PHPV than other breeds among dogs that underwent liver biopsy (P < 0.001 ...

Persistent hyperplastic primary vitreous (PHPV) syndrome associated with either severe ocular complications or multiple ocular lesions was diagnosed in three young dogs, a Samoyed, a Spanish Pachon, and a mixed breed dog.

2010年1月19日 · Persistent hyperplastic tunica vasculosa lentis (PHTVL) and persistent hyperplastic primary vitreous (PHPV) Begins in utero, with progressive atrophy of the vascular system that supports the eye lens; Common in Briards, Cocker Spaniels, beagles, rottweilers; Retinal dysplasia Appears as folds or rosette shapes on the retina; Common in Briards