2024年12月25日 · PIGS (Phosphatidylinositol Glycan Anchor Biosynthesis Class S) is a Protein Coding gene. Diseases associated with PIGS include Developmental And Epileptic Encephalopathy 95 and Opitz-Kaveggia Syndrome .

GPI transamidase component PIG-S is an enzyme that in humans is encoded by the PIGS gene. [5] . This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface.

The PIGOME is a searchable, multi-omics database for the functional genomic studies in pigs, comprising 7 data types and nearly 7000 datasets, spanning 113 breeds, 71 tissues and 29 developmental stages.

In this Special Issue, we will present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances.

2024年1月4日 · We build a pig genotype imputation panel and associate millions of genetic variants with five types of transcriptomic phenotypes in 34 tissues. We evaluate tissue specificity of regulatory...

2012年11月14日 · Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia....

2024年1月5日 · To fully unlock the potential of pigs as both agricultural species for animal-based protein food and biomedical models for human biology and disease, a comprehensive understanding of molecular and cellular mechanisms underlying various complex phenotypes in pigs and how the findings can be translate …

2021年10月6日 · We demonstrate that genomic variants associated with complex traits and adaptive evolution in pig are significantly enriched in active promoters and enhancers. Furthermore, we reveal distinct...

The Pig Genome Database (PGD) is to serve the purpose not only to bring together pig gene expression, quantitative trait loci (QTL), candidate gene, and whole genome association study (WGAS) results, but also to facilitate information integration …

In this study, we generated a pangenome of pigs and a genome variation map of 599 deep-sequenced genomes across Eurasia. Moreover, a section-wide gene repertoire was constructed, which indicated that core genes were more evolutionarily conserved than variable genes.