2024年9月18日 · Gene ID: 843432, updated on 18-Sep-2024. A regulator of auxin efflux and involved in differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at the lateral cell surface. PIN3 localizes to …

2022年8月2日 · In this study, we present structures of A. thaliana PIN3 in the apo state and in complex with the substrate IAA or the inhibitor NPA and provide structural insights into the molecular basis of...

2002年2月14日 · Mutations in the Arabidopsis gene PIN3, a regulator of auxin efflux, alter differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at...

PIN proteins are integral membrane proteins in plants that transport the anionic form of the hormone auxin across membranes. [1][2] The discovery of the initial member of the PIN gene family, PIN1, occurred through the identification of the pin-formed1 (pin1) mutation in …

A regulator of auxin efflux and involved in differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane and to vesicles.

2009年12月29日 · PIN genes are found exclusively in the genomes of multicellular plants and play an important role in regulating asymmetric auxin distribution in multiple developmental processes, including embryogenesis, organogenesis, tissue differentiation and tropic responses.

2023年8月19日 · We found that auxin synthesis gene TAA1 and auxin polar transport genes AUX1 and PIN3 collectively maintain fertility and seed size in Arabidopsis. Auxin plays a vital role in plant gametophyte development and embryogenesis.

Within the PIN family, PIN3 exhibits a prominent ability to change its subcellular localization in response to gravity and light. In the columella cells of the root tip, where perception of gravity occurs (Chen et al., 1999), PIN3 is localized to the plasma membrane in an apolar manner

The dimeric PIN3 forms a large, joint extracellular-facing cavity at the dimer interface while each subunit adopts an inward-facing conformation. The structural and functional analyses, along with computational studies, reveal the structural basis for the recognition of indole-3-acetic acid and NPA and elucidate the molecular mechanism of NPA ...

2018年7月6日 · In this study we examined potential phosphorylation sites in the PIN3 hydrophilic loop and their role in tropic responses.