Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone -containing quinolones. It was introduced in 1979 and is active against gram negative and some gram positive bacteria. It was used for gastrointestinal, biliary, and urinary infections. [1] .

Pipemidic acid is a pyridopyrimidine that is 5-oxo-5,8-dihydropyrido [2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.

Pipemidic acid is a quinolone antibiotic indicated in the treatment of susceptible urinary tract infections.

Pipemidic Acid is a quinolone antibacterial agent. It’s used in the treatment of urinary tract infections, recidive cystitis, prolongation of the therapy of pyelonephritis (prolonged therapy at patients with tendency to recidives.

Pipemidic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-pyrido [2,3-d]pyrimidine-6-carboxylic acid, is a new derivative of piromidic acid. It is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria.

Pipemidic acid (HPPA) is a quinolone antibacterial agent used mostly to treat gram-negative infections of the urinary tract, but its therapeutic use is limited because of its low solubility. Thus, to improve drug solubility, natural cyclodextrins ...

Asymptomatic bacteriuria is common during pregnancy. Perhaps ⅓ of affected pregnant women will develop symptomatic disease (hemorrhagic cystitis or pyelonephritis). Nalidixic acid is one treatment alternative for asymptomatic bacteriuria of pregnancy.

2025年1月7日 · Pipemidic Acid is a quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Pipemidic Acid is also used to associated treatment for these conditions: Urinary Tract Infection. *** Taking medicines without …

Pipemidic acid, a structural relative of piromidic and nalidixic acids, exhibited substantial therapeutic activity when it was administered orally to mice bearing either widely disseminated or relatively localized infections with Staphylococcus aureus and a variety of gram-negative bacilli.

Pipemidic acid is used to study DNA damage and mutagenic activity. It has been used to induce articular lesions in the neonatal mouse and is used to study human lymphocyte blastogenesis and γ-interferon production .