2024年12月25日 · PITX1 (Paired Like Homeodomain 1) is a Protein Coding gene. Diseases associated with PITX1 include Clubfoot, Congenital, With Or Without Deficiency Of Long …

Paired-like homeodomain 1 is a protein that in humans is encoded by the PITX1 gene. [5][6][7] This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class …

The PITX1 gene provides instructions for making a protein that plays a critical role in development of the lower limbs. The PITX1 protein is found primarily in the developing legs and feet. The …

2021年12月13日 · We find that the over-representation of Pitx1 non/low-expressing cells originates from a failure of the Pitx1 locus to coordinate enhancer activities and 3D chromatin …

In mouse, Pitx1 regulates hindlimb tissue patterning and pituitary development. Pitx2 is essential for the development of the oral cavity and abdominal wall while regulates the formation and …

2021年9月15日 · Here we show that paired-like homeodomain transcription factor 1 (PITX1) plays a crucial role in the inhibition of melanoma progression through regulation of SRY-box …

2021年4月12日 · In mouse, Pitx1 regulates hindlimb tissue patterning and pituitary development. Pitx2 is essential for the development of the oral cavity and abdominal wall while regulates the …

该基因编码 RIEG/PITX 同源盒家族的一个成员，该家族属于同源域蛋白的二元类。 这个家族的成员参与器官发育和左右不对称。 这种蛋白质作为参与催乳素基础和激素调节活性的转录调节 …

Expression of Pitx1 in the adult pituitary is primarily in the corticotrophs, regulating POMC expression synergistically with Tpit. Pitx1 also appears to modulate Sf1 activity in …

Combining gene targeting with chromatin immunoprecipitation sequencing (ChIP-seq) and transcriptomic analyses reveals that PITX1 cooperates with SOX2 and TRP63 to sustain an …