The induction of H3K9 methylation by PIWIL4 at the p16
2007年8月3日 · Moreover, the PIWI-like family localized to the nuclear periphery, and the transient transfection of PIWIL4 induced H3K9 methylation at the p16 Ink4a (CDKN2A) locus, …
PIWI-interacting RNAs: small RNAs with big functions
2018年11月16日 · In flies, Piwi promotes H3K9 methylation, a repressive chromatin mark, through recruitment of Eggless (also known as dSetdb1) by the Piwi-interacting mediator proteins …
PIWI proteins and PIWI-interacting RNAs in the soma - Nature
2014年1月15日 · Through an unknown mechanism, a critical mass of the H3K9 repressive chromatin marks inhibits Pol II transcription, effectively silencing the Piwi–piRNA target.
RNA-mediated epigenetic regulation of gene expression
2015年1月2日 · In Drosophila melanogaster, recent evidence suggests the existence of a self-reinforcing relationship between Piwi-interacting RNA (piRNA) biogenesis and histone H3 …
The control of gene expression and cell identity by H3K9 …
The Piwi complex interacts with the SUMO E3 ligase Su(var)2-10 (Sv210), which is auto-SUMOylated and may also induce the SUMOylation of additional chromatin factors. The …
Piwi Is Required during - Cell Press
2017年5月4日 · Piwi embryonic expression is needed for dual-strand piRNA cluster identity establishment that is required, in ovaries, for cluster H3K9 trimethylation (and Rhino binding), …
The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus
2007年8月3日 · Transient transfection of PIWI-like 4 (PIWIL4), only member of the PIWI-like family that was ubiquitously expressed in human tissues, induced histone H3 lysine 9 …
The induction of H3K9 methylation by PIWIL4 at the p16Ink4a …
2007年9月1日 · Transient transfection of PIWI-like 4 (PIWIL4), only member of the PIWI-like family that was ubiquitously expressed in human tissues, induced histone H3 lysine 9 …
Piwi and piRNA in Germline and Epigenetic Regulation
2024年5月3日 · Upon encountering a complementary transposon RNA transcript, Piwi recruits chromatin factors like histone methyltransferase (HMT) to deposit repressive methylated H3K9 …
Piwi Modulates Chromatin Accessibility by Regulating Multiple …
2016年8月4日 · In Drosophila ovaries, Piwi-piRNA complexes (Piwi-piRISCs) repress TE transcription by modifying the chromatin state, such as by H3K9 trimethylation. Here, we …