The cellular and molecular basis for planarian regeneration
Planarians are flatworms capable of dramatic feats of regeneration, which have been studied for over two centuries. Recent findings identify key cellular and molecular principles underlying these feats.
The Cellular and Molecular Basis for Planarian Regeneration
2018年10月4日 · Planarians are flatworms capable of dramatic feats of regeneration, which have been studied for over 2 centuries. Recent findings identify key cellular and molecular principles underlying these feats.
Stem cell systems and regeneration in planaria - PMC
The de novo regeneration of the planarian eye via the coalescence of individually migrating progenitors arising far from their target site provides a striking example of self-organization (Lapan and Reddien 2011). Assembling a structure as complex as the eye necessitates both multiple cell fate choices and precise spatial arrangements of cells.
The Cellular and Molecular Basis for Planarian Regeneration
2018年10月4日 · Planarians are flatworms capable of dramatic feats of regeneration, which have been studied for over 2 centuries. Recent findings identify key cellular and molecular principles underlying these feats.
The Cellular and Molecular Basis for Planarian Regeneration
Planarians are flatworms capable of dramatic feats of regeneration, which have been studied for over 2 centuries. Recent findings identify key cellular and molecular principles underlying these feats.
Spatiotemporal transcriptomic atlas reveals the dynamic ... - Nature
2023年6月2日 · Here, we present a comprehensive three-dimensional spatiotemporal transcriptomic landscape of planarian regeneration. We describe a pluripotent neoblast subtype, and show that depletion of its...
m6A promotes planarian regeneration - PMC - National Center …
2023年4月21日 · Regeneration is the regrowth of damaged tissues or organs, a vital process in response to damages from primitive organisms to higher mammals. Planarian possesses active whole‐body regenerative capability owing to its vast reservoir of adult stem cells, neoblasts, providing an ideal model to delineate the underlying mechanisms for regeneration.
Planarian Regeneration as a Model of Anatomical Homeostasis: …
Amputated fragments of planaria regenerate a complete worm, growing precisely what is missing – no more and no less – with events at the wound edge coordinated tightly with body-wide remodeling of the intact tissue to ensure that a perfectly proportioned animal results within about a week after it is cut along any plane . Every piece of a ...
Stem cells (neoblasts) and positional information jointly dominate ...
4 天之前 · The remarkable regeneration ability of planarians is conferred by an abundant population of adult stem cells called neoblasts. Neoblasts account for 20–30% of the cells in adult worms, and are dispersed broadly throughout the body except the tip of the head and pharynx, the only two body parts that are incapable of regeneration [14], [22], [23]. ...
Stem cells (neoblasts) and positional information jointly dominate ...
5 天之前 · Regeneration is the ability to accurately regrow missing body parts. The unparalleled regenerative capacity and incredible tissue plasticity of planarians, both resulting from the presence of abundant adult stem cells referred to as neoblasts, offer a unique opportunity to investigate the cellular and molecular principles underlying regeneration. Neoblasts are capable of self-renewal and ...