2024年12月25日 · PLAU (Plasminogen Activator, Urokinase) is a Protein Coding gene. Diseases associated with PLAU include Quebec Platelet Disorder and Alzheimer Disease, Familial, 1. …

Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not …

2025年1月4日 · Title: PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway. Involvement of matrix metalloproteinase 1 and urokinase-type …

PLAU is a promising new candidate gene for late-onset Alzheimer's disease, with allele C (P141) being a recessive risk allele or allele T (L141) conferring protection. u-PA down-regulation by …

2025年1月4日 · Clinical resource with information about PLAU, Alzheimer disease type 1, Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease., …

2021年5月20日 · Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. However, the biological functions and …

Elevated PLAU correlates with increased aggressive phenotypes, stromal score, and immune suppression in PDAC. PLAU upregulation is also closely associated with the basal subtype …

2023年8月28日 · PLAU is a protease that converts plasminogen to plasmin. It appears to affect murine ageing: its overexpression in the brain diminishes food consumption and extends …

Urinary plasminogen activator (uPA, PLAU; EC 3.4.21.73) converts plasminogen (173350) to plasmin. Urokinase has a molecular mass of about 54 kD and is composed of 2 disulfide …

2017年3月16日 · Quebec Platelet disorder (QPD) is a unique bleeding disorder that markedly increases urokinase plasminogen activator (uPA) in megakaryocytes and platelets but not in …