2024年12月25日 · PLIN5 (Perilipin 5) is a Protein Coding gene. Diseases associated with PLIN5 include Hyperinsulinemic Hypoglycemia, Familial, 5 and Chanarin-Dorfman Syndrome . Gene …

Perilipin 5 (Plin5) is a lipid droplet (LD) targeting protein that promotes association of LDs with mitochondria and is most highly expressed in oxidative tissues, including cardiac and skeletal …

We examine recent in vivo studies and ask whether the evidence from the cell biology approaches is consistent with the physiological roles of PLIN5. Keywords: animal physiology; lipid droplet; …

2023年7月24日 · We demonstrate that efficient LD-to-mitochondria fatty acid (FA) trafficking and ß-oxidation during starvation of myoblasts are promoted by phosphorylation of PLIN5 and …

2022年3月31日 · Plin5 may play a bidirectional function in lipid metabolism which is in a state of dynamic balance. In the basic state, Plin5 inhibited the binding of comparative gene …

2016年5月2日 · Perilipin 5 (Plin5) is a newly identified LD protein in the perilipin family, which plays a key role in regulating aspects of intracellular trafficking, signaling, and...

2025年2月8日 · Plin5 Bidirectionally Regulates Lipid Metabolism in Oxidative Tissues. Enlarged PLIN5-uncoated lipid droplets in inner regions of skeletal muscle type II fibers associate with …

In recent years, studies have shown that Plin5 expression is involved in the pathogenesis of DC lipid toxicity, such as oxidative stress, mitochondrial dysfunction, endoplasmic reticulum (ER) …

We found that among the perilipin proteins studied, perilipin 5 (Plin5; also known as LSDP5) is uniquely associated with mitochondria in oxidative cells and tissues, especially heart, and that …

2022年4月25日 · Lipid toxicity is an important pathogenic factor due to abnormal lipid accumulation in DC. As a lipid droplet (LD) decomposition barrier, Plin5 can protect LDs from …