2024年12月25日 · PLLP (Plasmolipin) is a Protein Coding gene. Diseases associated with PLLP include Febrile Seizures, Familial, 6 and Usher Syndrome, Type Iiia. An important paralog of this gene is CMTM8. Appears to be involved in myelination.

2025年1月4日 · These data support a model in which PLLP functions in myelin biogenesis through organization of myelin liquid-ordered membranes in the Golgi complex. Title: The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex. A genome-wide association study of sleep habits and insomnia.

The BBS2 gene (16q13–21) is in the long arm of human chromosome 16 together with PLLP (16q13). Its mutations cause Bardet–Biedl syndrome type 2, which is a rare autosomal dominant hereditary disorder with polymorphic clinical signs, including cone-rod retinal dystrophy, obesity, renal dysfunction, and intellectual impairments.

2021年12月17日 · The proteolipid plasmolipin (PLLP) is a possible marker. PLLP is a main component of the myelin sheath and plays an important role in the development and normal function of the nervous system. PLLP is involved in intracellular transport, lipid raft formation, and Notch signaling.

2025年2月19日 · Structure of the Myelin Sheath Proteolipid Plasmolipin (PLLP) in a Ganglioside-Containing Lipid Raft. Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosis. These data support a model in which PLLP functions in myelin biogenesis through organization of myelin liquid-ordered membranes in the Golgi complex.

V5 expression in the membrane is high than intracellular expression. The PLLP gene is one of the many genes being observed and studied in the IDG project.

General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full …

This gene has 5 transcripts (splice variants), 201 orthologues and 14 paralogues. Broad expression in brain (RPKM 41.3), stomach (RPKM 28.7) and 17 other tissues. 功能概要

2016年9月14日 · Gene target information for PLLP - plasmolipin (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

2024年9月12日 · PLLP plasmolipin Gene ID: 51090, updated on 12-Sep-2024 Gene type: protein coding Also known as: PMLP; TM4SF11. See all available tests in GTR for this gene; Go to complete Gene record for PLLP; Go to Variation Viewer for PLLP variants; Summary. Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination.