2024年12月25日 · POGZ (Pogo Transposable Element Derived With ZNF Domain) is a Protein Coding gene. Diseases associated with POGZ include White-Sutton Syndrome and Nail …

2021年9月16日 · White-Sutton syndrome is an autosomal dominant disorder typically caused by a de novo pathogenic variant. Most probands reported to date whose parents have undergone …

The POGZ gene provides instructions for making a protein that is found in the cell nucleus. The POGZ protein is part of a group known as zinc finger proteins, which contain one or more …

Pogo transposable element with ZNF domain is a protein that in humans is encoded by the POGZ gene. [5][6] The protein encoded by this gene appears to be a zinc finger protein containing a …

2020年2月26日 · Pogo transposable element derived with ZNF domain (POGZ) has been identified as one of the most recurrently de novo mutated genes in patients with …

Analyses of pogz knockout mice revealed that the POGZ protein promotes chromatin accessibility and expression of clustered synapse genes, and co-occupies loci with ADNP, a gene …

The mutation, which was found by next-generation sequencing of the POGZ gene in 764 patients with neurodevelopmental disorders, was confirmed by Sanger sequencing and filtered against …

Gene ID: 23126, updated on 8-Feb-2025. The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to …

Deleterious genetic variants in POGZ, which encodes the chromatin regulator Pogo Transposable Element with ZNF Domain protein, are strongly associated with autism spectrum disorder …

This gene was identified in Iossifov et al. 2015 as a strong candidate to be an ASD risk gene based on a combination of de novo mutational evidence and the absence or very low …