作者提出，poss 纳米粒子与软 pcu 段和硬 pcu 段结合在一起，形成一个单一的弹性基质，这使得纳米复合材料能够抵抗水解、氧化和钙化。 POSS 提高了拉伸强度（高达 53.6 ± 3.4 N mm^(-2) 对比 PCU 中的 33.8 ± 2.1 N mm^(-2)，p < 0.01）和所得材料的疏水性。

2015年1月1日 · A family of nanocomposite polymers based on polyhedral oligomeric silsesquioxane (POSS) nanoparticles incorporated in to poly (carbonate-urea) urethane (PCU) has been synthesized for use in a wide range of surgical implants, and was developed and patented by the University College London (POSS-PCU) [5].

The enhanced biocompatibility, superior mechanical engineering properties, and augmented degradative resistance of POSS-PCU render it capable of functioning as a scaffold for bioartificial organs, nanoparticles for biomedical applications, and a coating for medical devices.

We have developed a novel nanocomposite polymer emulsion based on polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS–PCU) that can be used to coat quantum dots to nullify their toxicity and enhance photostability.

We describe optimization of POSS-PCU by dispersion of porogens (sodium bicarbonate (NaHCO3), sodium chloride (NaCl) and sucrose) onto the material surface, with the principle aim of increasing surface porosity, thus providing additional opportunities for improved cellular and vascular ingrowth.

In this study, the mechanical properties of POSS-PCU, including tensile strength, tear strength and hardness, were tested and compared to control (PCU). The surface property was analyzed using contact angle measurement and the resistance to platelet adhesion was also investigated.

2016年3月1日 · We describe optimization of POSS-PCU by dispersion of porogens (sodium bicarbonate (NaHCO 3), sodium chloride (NaCl) and sucrose) onto the material surface, with the principle aim of increasing surface porosity, thus providing additional opportunities for improved cellular and vascular ingrowth.

2013年8月23日 · Herein, we describe the preparation and characterization of a novel polyhedral oligomeric silsesquioxane poly (carbonate-urea) urethane (POSS-PCU) nanocomposite polymer with covalently attached anti-CD34 antibodies to enhance capture of circulating endothelial progenitor cells (EPC).

The scaffolds from non-treated POSS-PCU, Ar plasma-treated POSS-PCU, and commercial Medpor ® porous polyethylene have been investigated by various methods. Protein adsorption, Human Dermal Fibroblast seeding, and assessment of their morphology, adhesion, growth, and secretion of collagen and VEGF have been performed.

2015年12月16日 · We have developed a novel nanocomposite polymer emulsion based on polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU) that can be used to coat quantum dots to nullify their toxicity and enhance photostability.