2024年12月25日 · PPIA (Peptidylprolyl Isomerase A) is a Protein Coding gene. Diseases associated with PPIA include Influenza and Measles. Among its related pathways are HIV Life Cycle and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include RNA binding and peptide binding.

Peptidylprolyl isomerase A (PPIA), also known as cyclophilin A (CypA) or rotamase A is an enzyme that in humans is encoded by the PPIA gene on chromosome 7.

2021年10月5日 · The present study identified Ppia as the best housekeeping gene for CY + NC and SC + CO groups, while Hprt was the best for the HT + WT group.

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans is omerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression.

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression.

这个基因编码肽基-脯氨酰顺反异构酶 (PPIase)家族的成员。 PPIases催化寡肽中脯氨酸亚胺肽键的顺反异构化，并加速蛋白质的折叠。 编码的蛋白质是环孢素结合蛋白，可能参与环孢素A介导的免疫抑制。 该蛋白质还可以与几种HIV蛋白质相互作用，包括p55 gag、Vpr和衣壳蛋白，研究表明对于感染性HIV病毒粒子的形成是必要的。 已经报道了多个定位于不同染色体上的假基因。 [由RefSeq，2008年7月提供] Dir./Indir. The DNA sequence of human chromosome 7. Proteomic …

2024年10月28日 · Title: Ppia is the most stable housekeeping gene for qRT-PCR normalization in kidneys of three Pkd1-deficient mouse models. Interleukin 37 (IL-37) Reduces High Glucose-Induced Inflammation, Oxidative Stress, and Apoptosis of Podocytes by Inhibiting the STAT3-Cyclophilin A (CypA) Signaling Pathway.

2016年9月14日 · This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins.

2025年2月9日 · This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression.

Enables Integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space and myelin sheath. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; liver; and skeletal muscle.