2024年12月25日 · PPP5C (Protein Phosphatase 5 Catalytic Subunit) is a Protein Coding gene. Diseases associated with PPP5C include Microcephaly, Seizures, And Developmental Delay and Breast Cancer. Among its related pathways are MAPK family signaling cascades and ESR-mediated signaling.

Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene. [5] [6]

2023年6月5日 · Protein phosphatase 5 (PPP5C) is a serine/threonine protein phosphatase showing dual function by simultaneously exerting dephosphorylation and co-chaperone functions. Due to this special role, PPP5C was found to participate in many signal transductions related to various diseases.

Protein phosphatase 5 (PPP5C) is a serine/threonine protein phosphatase showing dual function by simultaneously exerting dephosphorylation and co-chaperone functions. Due to this special role, PPP5C was found to participate in many signal transductions related to various diseases.

structure of Serine/threonine protein phosphatase-5 (PP5c) provides a structural basis for explaining the exceptional catalytic proficiency of protein phosphatases. This gene encodes a serine/threonine phosphatase which is a member of the …

Protein phosphatase 5 (PPP5C) is a serine/threonine protein phosphatase showing dual function by simultaneously exerting dephosphorylation and co-chaperone functions. Due to this special role, PPP5C was found to participate in many signal transductions related to various diseases.

Ubiquitous expression in heart (RPKM 18.5), brain (RPKM 17.4) and 25 other tissues. 该基因编码丝氨酸/苏氨酸磷酸酶，它是蛋白磷酸酶催化亚基家族的成员。 该家族中的蛋白质参与由丝氨酸和苏氨酸残基可逆磷酸化调节的途径；其中许多途径都参与细胞生长和分化的调节。 该基因的产物已被证明参与响应激素或细胞应激的信号通路，并且该蛋白质水平升高可能与乳腺癌的发展有关。 可变剪接导致多个转录本变体。 [RefSeq 提供，2011 年 2 月]

2023年6月5日 · Protein phosphatase 5 (PPP5C) is a serine/threonine protein phosphatase showing dual function by simultaneously exerting dephosphorylation and co-chaperone functions. Due to this special role, PPP5C was found to participate in many signal transductions related to various diseases.

2024年8月16日 · FUNCTION: May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1. CATALYTIC ACTIVITY: A phosphoprotein + H (2)O = a protein + phosphate. COFACTOR: Binds 1 iron ion per subunit (By similarity).

2018年9月12日 · Serine/threonine protein phosphatase 5 (PPP5C) is a vital molecule that Involve in complex cell physiological activity. Purpose: The objective of this study was to detecte the expression level of PPP5C in the tissue of prostate cancer patients and further discussed the PPP5C biological function and mechanisms on the PCa.