2024年11月14日 · Symptoms of Prader-Willi syndrome, which can vary, slowly change over time from childhood to adulthood. Symptoms that may be present from birth include: Poor muscle tone. A main sign during infancy is poor muscle tone, also known as hypotonia. Babies may rest with their elbows and knees loosely extended instead of fixed.

Prader-Willi syndrome (PWS) is a complex neurodevelopmental disease that is caused by absence of paternal expressed imprinting genes at chromosome 15q11–13 region.

Due to advances in research and hormone replacement therapy, many of the younger adults with PWS may look different and face less challenges than older adults. It affects both males and females equally and in all races around the world. The prevalence range is …

2022年8月25日 · Adults with Prader-Willi syndrome (PWS) can live full, active lives when given the right support. For many people living with PWS, this can mean joining a club or volunteering in their community. Some may need more support than others, especially if …

The GP can play an important role in identifying Prader-Willi syndrome among adult patients who may have remained undiagnosed. Specific care and treatments can then be provided in the general practice setting.

Maladaptive behavior has been reported as a phenotypical feature in Prader–Willi syndrome (PWS). It severely limits social adaptation and the quality of life of children and adults with the syndrome. Different factors have been linked with the intensity and form of these behavioral disturbances but there is no consensus about the cause.

2024年4月12日 · Prader-Willi syndrome (PWS) is a rare genetic syndrome marked by low muscle tone, below average growth in infancy, excessive appetite, and low muscle mass in adulthood. First identified in...