This chapter will focus on the diagnostic gross features of select nonhuman primate neoplasms complemented by histology and a basic overview of each neoplastic entity. Since a detailed overview of all nonhuman primate neoplasia is outside of the scope of this chapter, we refer the reader to other resources for more comprehensive overviews .

2024年5月13日 · The Atlas of Diagnostic Pathology in Nonhuman Primates offers the first extensively illustrated collection of classic lesions in nonhuman primate diseases and pathological conditions, compiled by an international team of expert contributors. Organized by infectious and noninfectious conditions, the atlas comprehensively covers viral, bacterial ...

Neoplasia of the gastrointestinal system is the most commonly diagnosed in rhesus macaques with adenocarcinoma of the large intestines as most prevalent tumor. 47: Symptoms: Similar clinical signs as in humans including weight loss, intermittent diarrhea, hypoproteinemia, fecal occult blood, and microcytic anemia. 47 75 77 78: Location

Understanding causes of morbidity and mortality in nonhuman primates is essential for maintaining these species in captivity and managing populations in the wild. Although it has been stated that neoplasia is relatively uncommon in nonhuman primates [21, 88], more recent reports and excellent review articles suggest that as the age of captive ...

Endometriosis was the most frequently diagnosed lesion of the female genital tract, occurring primarily in Old World primates. Leiomyoma was the most common uterine tumor. Granulosa cell tumor was the most frequently observed neoplasm of the ovaries, followed by teratoma. Of animals included in the study, most ovarian tumors occurred in baboons.

Three cases are primary lingual tumors: chondro-osteoblastic lipoma in a howler monkey, squamous cell carcinoma, and fibroma in two baboons. We describe two cases of metastatic lymphoma in the tongue in rhesus macaques. A literature review of published lingual neoplasia in nonhuman primates is included in this manuscript.

2021年1月5日 · Nonhuman primates, particularly macaque species, may serve as a highly translational animal model in breast cancer studies due to their similarity with humans in genetics, anatomy, reproductive and endocrine physiology including mammary gland development profile.

2024年7月21日 · Through a multi-institutional retrospective study we compile cases of primary and metastatic neoplasia in non-human primates. We describe five cases of lingual neoplasia. Three cases are primary lingual tumors: chondro-osteoblastic lipoma in a howler monkey, squamous cell carcinoma, and fibroma in two baboons.

The study of neoplasia in nonhuman primates provides a unique opportunity to gain insights into the mechanisms of tumorigenesis and to compare these with human cancer development. In addition, the observation of neoplasms in nonhuman primates can expand the understanding of the impact of environmental and lifestyle factors on cancer risk.

2021年1月5日 · Nonhuman primates, particularly macaque species, may serve as a highly translational animal model in breast cancer studies due to their similarity with humans in genetics, anatomy, reproductive and endocrine physiology including mammary gland development profile.