Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.

2024年12月25日 · PRKCA (Protein Kinase C Alpha) is a Protein Coding gene. Diseases associated with PRKCA include Male Infertility Due To Globozoospermia and Hematologic Cancer.Among its related pathways are Prolactin Signaling and Calmodulin induced events.Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase ...

Protein kinase C alpha (PKCα) is an enzyme that in humans is encoded by the PRKCA gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol.

2025年2月9日 · Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.

Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected. The RNA data was used to cluster genes according to their expression across cell lines.

蛋白激酶C（PKC）是一类特异性的丝氨酸和苏氨酸蛋白激酶家族，可以通过钙离子和第二信使二酯酰甘油激活。 PKC家族成员可以磷酸化各种蛋白质靶标，并已知参与多种细胞信号传导途径。 PKC家族成员还作为佛波酯类的一类肿瘤促进剂的主要受体。 PKC家族每个成员都有特定的表达模式，并被认为在细胞中扮演独特的角色。 这个基因编码的蛋白质是PKC家族成员之一。 这个激酶已被报道在许多不同的细胞过程中发挥作用，如细胞粘附、细胞转化、细胞周期检查点以及细 …

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.

Enables calcium-dependent protein kinase C activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; protein phosphorylation; and regulation of vesicle-mediated transport. Located in several cellular components, including membrane raft; mitochondrion; and perinuclear region of cytoplasm.

2024年2月12日 · Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.

2022年7月1日 · 蛋白激酶C（PKC）是一个丝氨酸和苏氨酸特异性蛋白激酶家族，可被钙和第二信使甘油二酯激活pkc家族成员磷酸化多种蛋白质靶点，参与多种细胞信号传导途径。 PKC家族成员也是一类肿瘤促进剂佛波酯的主要受体pkc家族的每个成员都有一个特定的表达谱，并被认为在细胞中发挥着独特的作用。 该基因编码的蛋白是pkc家族成员之一。 据报道，这种激酶在许多不同的细胞过程中发挥作用，如细胞粘附、细胞转化、细胞周期检查点和细胞体积控制。 小鼠的基 …