Bioactivities, preparation, and bioavailability of food-derived proline ...
Due to the unique structure of proline (Pro), Pro-containing peptides (PCPs) are endowed with specific conformational and physiological properties. There has been an increasing interest in the health-promoting effects of PCPs from dietary proteins.
Proline-rich peptides: multifunctional bioactive molecules as …
Proline-rich peptides (PRPs) include a large and heterogeneous group of small-medium sized peptides characterized by the presence of proline residues often constituting peculiar sequences. This feature confers them a typical structure that determines the various biological functions endowed by these …
Novel Arginine- and Proline-Rich Candidacidal Peptides …
2023年2月26日 · In this study, a search for new arginine- and proline-rich peptides from plants has been carried out with a bioinformatic approach by sequence alignment and antimicrobial prediction tools. Two peptide candidates were tested against planktonic cells and biofilms of Candida albicans and Candida glabrata strains, including resistant isolates.
Proline specific peptidases - ScienceDirect
1997年12月5日 · Proline containing bioactive peptides, conforming to the substrate specificity requirements of PO, and known to be hydrolysed by the enzyme, are listed in Table 1.
Proline-Rich Peptides: Multifunctional Bioactive Molecules As …
2015年1月2日 · Proline-rich polyproline peptides, especially left-handed structures, have been documented as indispensable for the presentation of antimicrobial,...
Proline- and Arginine-Rich Peptides Constitute a Novel Class of ...
2003年7月4日 · Recent studies demonstrated that PR39, a natural proline- and arginine-rich antibacterial peptide, stimulates angiogenesis and inhibits inflammatory responses by specifically blocking degradation of IκBα and HIF-1α by the proteasome. However, molecular events involved in the PR39−proteasome interaction have not been elucidated.
C9orf72-derived arginine-containing dipeptide repeats
Cargo transport defects are recapitulated by treating neurons from healthy individuals with proline-arginine and glycine-arginine dipeptide repeats (DPRs) produced from the repeat expansion. Both arginine-rich DPRs similarly inhibit axonal trafficking in adult Drosophila neurons in vivo.
Molecular Basis for Proline- and Arginine-Rich Peptide …
2008年12月5日 · The results provide prerequisites for proteasome inhibition by proline- and arginine-rich peptides, providing a powerful new tool to investigate inflammatory processes. These findings offer new leads in developing drugs to treat heart diseases or stroke.
Proline‐containing peptides—New insight and implications: A …
2019年8月19日 · Proline, the product of prolidase activity, modulates intracellular energetic status via Akt/mTOR pathway, inhibits HIF-1α degradation, and mediates in proline cycle, regulating...
In this study, a search for new arginine- and proline-rich peptides from plants has been carried out with a bioinformatic approach by sequence alignment and antimicrobial prediction tools....