ProTox 3.0 incorporates molecular similarity, fragment propensities, most frequent features and (fragment similarity based CLUSTER cross-validation) machine-learning, based a total of 61 models for the prediction of toxicity endpoints such as acute toxicity, organ toxicity, toxicological endpoints, molecular initiating events, metabolism ...

PROSTOX helps prostate cancer patients avoid toxicity from radiation therapy. Our first microRNA-based tests are for prostate cancer patients who are being offered radiation …

ProTox 3.0 Model Descriptions. Please select a model : Last updated: May 2024 Disclaimer: Compound structures submitted will not be released under any circumstances. This work is licensed under a ...

ProTox 3.0 is a free web service and the user can create a toxicity prediction for an input compound within a few minutes. Computational toxicity predictions can help to reduce the amount of animal experiments and save animal lives.

ProTox-II provides a freely available webserver for in silico toxicity prediction for toxicologists, regulatory agencies, computational and medicinal chemists, and all users without login at http://tox.charite.de/protox_II.

2024年4月22日 · The ProTox 3.0 web server provides several advantages over existing computational models. ProTox webserver includes chemical, molecular target knowledge, metabolism, and the Adverse outcomes pathways (AOPs).

2024年7月5日 · ProTox envisages itself as a complete, freely available computational platform for in silico toxicity prediction for toxicologists, regulatory agencies, computational chemists, and medicinal chemists.

PROTOX is a web server for the predictive toxicities of small molecules in rodents. It is designed for multiple input formats for chemicals either by generic name, structure, or chemical formula and classifies the chemical based on the programs reference database.

The ProTox 3.0 web server provides several advantages over existing computational models. ProTox webserver includes chemical, molecular target knowledge, metabolism, and the Adverse outcomes pathways (AOPs).

TOX predicts toxicity from two types of radiation therapy to the prostate: Stereotactic body radiation therapy (SBRT), where the radiation is delivered in high doses in 5-7 treatments, and conventionally fractionated radiation therapy (CFRT), where the radiation is …