Learn about the side effects of Protropin (somatrem), from common to rare, for consumers and healthcare professionals.

Somatrem was first marketed under the brand name Protropin by Genentech in 1985. [2] It differs from endogenous growth hormone by the addition of an extra methionine at the N-terminus [3] [circular reference]. Somatrem has largely been replaced by somatropin, marketed by several companies including by Genentech as the brand Nutropin.

Protropin® is a Revolutionary breakthrough in the field of oral HGH Enhancement that helps in the following ways: Increase in Muscle Mass; Increase in Strength; Increase in Physical Endurance; Increase in Recovery from Exercise; Anti-fatigue through lactic acid buffering; and Increased tolerance to workload.

PROTROPIN® Roche . Somatrem . Growth Hormone . Action And Clinical Pharmacology: Somatrem is a polypeptide (methionyl human growth hormone) produced by recombinant DNA technology using the gene for human growth hormone.

2010年6月1日 · The first available rhGH, protropin, was a polypeptide hormone produced by inclusion body recombinant DNA technology. Protropin had 192 amino acids and a molecular weight of 22 kDa. This molecule contained the identical sequence of 191 amino acids found in native pituitary hormone with the addition of a methionine (met-GH) on the N-terminus ...

2018年7月2日 · Somatrem and somatropin are trade names for synthetic versions of human growth hormone (Protropin) that are made by bacteria using recombinant DNA techniques. Protropin stimulates skeletal growth in those patients that have a growth hormone deficiency.

这使得FDA改变了态度，快速批准了该公司的重组生长激素（Protropin）。 得益于美国刚刚通过的《孤儿药法案》，用于侏儒症治疗的Protropin被认定为孤儿药，获得了七年的市场独占期，而且允许定高价。

Introduction to Protropin. Protropin is a recombinant pharmaceutical form of somatrem, a growth hormone (HGH) analog used for the treatment of growth hormone deficiency in children. Developed by Genentech, Protropin was the first biotech product approved for therapeutic use.

Protropin (somatrem) 生长激素（基因重组的生长激素） 简介： 基因重组生长激素是一种人工合成的人体生长激素（HGH）。它实际上是一种内源性hGH蛋白的变体，它与人体生长激素含有相同的191个氨基酸序列，但含有一个额外的氨基酸，蛋氨酸。

基因泰克被指控，其医药代表有时极力推荐 Protropin 用于未经批准的用途，甚至给开处方量大的医生变相地提供回扣。 1999年4月，基因泰克和联邦法院达成和解协议，支付给美国联邦5千万美元。