2022年8月21日 · PROVIT was conducted as a randomized, single-center, double-blind, placebo-controlled multispecies probiotic intervention study in individuals with MDD (n = 57). In addition to clinical assessments, metabolomics analyses (1H Nuclear Magnetic Resonance Spectroscopy) of stool and serum, and microbiome analyses (16S rRNA sequencing) were performed.

2020年11月8日 · Gut microbiota are suspected to affect brain functions and behavior as well as lowering inflammation status. Therefore, an effect on depression has already been suggested by recent research. The aim of this randomized double-blind controlled trial was to evaluate the effect of probiotic treatment in depressed individuals.

More precisely, PROVIT-CLOCK aimed to analyze the core clock gene expression (ARNTL, PER3, CLOCK, TIMELESS, NR1D1) in peripheral blood mononuclear cells (PBMCs) of fasting blood and the metabolome (NMR) in serum and stool samples of inpatients with MDD. In detail, the primary aim of the current inves-tigation of the PROVIT-CLOCK study was to ...

The PROVIT Metabolomics investigation is the first pilot study of probiotic RCT in individuals with MDD, which analyzes alterations in the metabolomic profiles of serum and stool. A major strength of the PROVIT study is that the patients were exposed to similar environmental stimuli, such as hospital food and physical activity.

provit 研究是一项随机、双盲、为期 4 周、多物种的益生菌干预研究，旨在阐明重度抑郁症 （mdd） 患者肠道代谢组与分子钟之间的潜在相互联系。 方法 PROVIT-CLOCK 研究的目的是分析益生菌干预与安慰剂治疗期间空腹血中核心时钟基因表达的变化，以及与 MDD 患者 ...

Polipéptidos de origen bovino y solución de cloruro de sodio estéril. Caja con 4 viales de liofilizado 2 ml c/u. PROVIT es un método terapéutico que utiliza péptidos obtenidos de organismos vivos para producir una estimulación específica sobre el órgano humano.

2022年8月21日 · PROVIT was conducted as a randomized, single-center, double-blind, placebo-controlled multispecies probiotic intervention study in individuals with MDD (n = 57). In addition to clinical...

2020年11月1日 · The PROVIT Study—Effects of Multispecies Probiotic Add-on Treatment on Metabolomics in Major Depressive Disorder—A Randomized, Placebo-Controlled Trial. Kathrin Kreuzer Alexandra Reiter +26 authors S. Bengesser

2020年11月8日 · Gut microbiota are suspected to affect brain functions and behavior as well as lowering inflammation status. Therefore, an effect on depression has already been suggested by recent research. The...

2020年11月8日 · Gut microbiota are suspected to affect brain functions and behavior as well as lowering inflammation status. Therefore, an effect on depression has already been suggested by recent research. The aim of this randomized double-blind controlled trial was to evaluate the effect of probiotic treatment in depressed individuals.